Reliance refers to the use of an institutional review board (IRB) outside of the University of Minnesota to conduct the regulatory review and oversight of a study.
Reliance arrangements can require a complex and lengthy negotiation process. The HRPP is responsible for negotiating and coordinating the execution of IRB reliance agreements. This includes obtaining review by legal counsel, as needed, and signature of the U of M institutional official.
Submit a reliance request if a project or study involves collaboration with sites or personnel outside of the University of Minnesota and you would like to use a single IRB for review of the research.
Use the following resources to prepare a reliance request:
How to submit a reliance request
Detailed, step-by-step guide on how to submit a reliance request.
Reliance agreement criteria
Detailed eligibility criteria for reliance requests.
Roles and responsibilities
Description of University and researcher roles and responsibilities for reliance studies.
Relying on Quorum—Coming Soon
Detailed instructions and guidance for relying on Quorum.
Frequently asked questions
Frequently received questions about reliance requests.
We also recommend reviewing the following documents from the HRPP Toolkit Library:
Comprehensive guide of all policies, procedures, and resources related to the conduct of human research at the University of Minnesota.