University Startups
We have launched more than 260 startups (video) based on UMN research since the Venture Center was formed in 2006, with more than $1.8 billion raised in investment capital, IPOs and acquisitions (2022 survey). Ten UMN startups have been acquired or have gone public since 2017, underscoring the relevance of University innovations and technologies.
- All
- Biotech & Pharmaceuticals
- Energy & Environment
- Engineering & Physical Science
- Food & Agriculture
- Medical Devices
- Software & IT
All
Description | |||||
|---|---|---|---|---|---|
| 276 | Biotech & Pharmaceuticals | Exomed Diagnostics | 2025 February | Saydam, Nurten | Develops therapies for glioblastoma and meningioma. |
| 275 | Software & Information Technology | SmartPal | 2025 February | De, Liu | AI student support plugin for Canvas and other learning management systems. |
| 274 | Engineering & Physical Science | LEAP Photonics, Inc. | 2025 January | Li, Mo | Advancing cost-effective, high-performance LiDAR solutions for automation and robotics. |
| 273 | Biotech & Pharmacy | Nanoli Therapeutics | 2024 November | Li, Fang | Developing nanobodies for various cancers and viral diseases. |
| 272 | Biotech & Pharmacy | KuriBio | 2024 November | Adamala, Katarzyna (Kate) | Developing liposomes with surface embedded receptors that express peptides to increase detectable cancer results in existing diagnostic tests. |
| 271 | Biotech & Pharmacy | NorthStar Cryo | 2024 November | Bischof, John | Developing methods and materials for the scaled preservation of small materials and cells for research and therapeutic purposes. |
| 270 | Biotech & Pharmacy | FKP Therapeutics | 2024 October | Prins, Kurt | Nanobody-Based Treatment for Right Ventricular Failure |
| 269 | Medical Devices | OralMR LLC | 2024 October | Nixdorf, Donald | Small, low cost, minimal viable dedicated dental MRI for imaging inflation and soft tissues. Company co-founders are Don Nixdorf and Beth Gronke |
| 268 | Food & Agriculture | ZaNe Genetics | 2024 October | Smanski, Michael | Use of large black soldier fly larva to produce omega-3 oils for use in dietary supplements. |
| 267 | Software & Information Technology | Emet Surgical, Inc. | 2024 October | Papanikolopoulos, Nikolaos | AI driven navigation system for tumor removal and tumor identification during minimally invasive surgery. |
| 266 | Medical Devices | GlioStim Medical Systems | 2024 September | Chen, Clark | Technology for treating solid tumors (founded by Joe Hofmeister) |
| 265 | Medical Devices | MotionMedix LLC | 2024 September | Ebbini, Emad; Aldiabat, Hasan; Casper, Andrew; Liu, Dalong; O'Brien, Parker | MotionMedix is using ultrasound imaging to measure hydration and biomarkers for the ICU and Sports Medicine. |
| 264 | Software & Information Technology | Social Value, Inc. | 2024 August | Srivastava, Jaideep & Khan, Euna | Leverages proprietary algorithm to develop software that augments marketing and social analytics for enhanced operations. |
| 263 | Engineering & Physical Science | Uniqomp, LLC | 2024 August | Bazargan, Kia | A field-programmable gate arrays for advanced mathematical functions useful in artificial intelligence, investment and finance, and robotics. |
| 262 | Biotech & Pharmaceuticals | Gavia Bio | 2024 August | Gorr, Sven-Ulrik | An anti-microbial hydrogel for treating chronic wounds, burns, and oral infections. The hydrogel directly attacks bacterial cell membranes to make them less susceptible to bacterial resistance. |
| 261 | Biotech & Pharmaceuticals | Crichton Biosciences | 2024 July | Verma, Vivek | Therapeutics for solid tumors by reversing cancer immunotherapy resistance through metabolic reprogramming. |
| 260 | Medical Devices | NeoAcoustic Inc | 2024 May | Lim, Hubert | Ultrasound hearing aid delivers ultrasound stimulation to present waves and vibrations in the brain fluids, which in turn vibrate cochlear fluids through the inner ear canal/aqueduct, thus activating the auditory brain and inducing hearing in the brain. |
| 259 | Biotech & Pharmaceuticals | CounterX Therapeutics Inc | 2024 April | Pravetoni, Marco | Vaccines and antibody therapeutics for treating opiate addiction addressing significant public health implications (e.g. fentanyl, heroine etc.) |
| 258 | Biotech & Pharmaceuticals | Itasca Therapeutics Inc | 2024 April | Various: Paul Robbins, Laura Niedernhofer, Laura Niedernhofer | Developing anti-aging therapeutics using small molecules that eliminate senescent cells to slow or reduce the aging effects. |
| 257 | Medical Devices | HiFi Imaging LLC | 2024 March | Akcakaya, Mehmet | MRI software and pulse sequences that leverage AI-based approaches to improve scan time, image quality, and acoustic noise on standard MRI scanners. |
| 256 | Medical Devices | Optimal Mobility LLC | 2024 March | McCracken, Patricia | Pediatric standup wheelchair. |
| 255 | Energy & Environment | Waypoint Forward | 2024 March | Various: Abigail Clarke-Sather, Paulo Alves | Clothing recycling solution that shreds textiles down to the fibers so that they are able to be respooled into new thread. |
| 254 | Biotech & Pharmaceuticals | 6D Biosystems | 2024 February | Panoskaltsis-Mortari, Angela | Commercializing the use of bioink and biological fibers for 3D tissue printing of in-vitro metastic testing models. |
| 253 | Medical Devices | Glome Health | 2024 February | Yekinni, Ibrahim | Prevents patients from developing infections from the connecting/disconnecting process during a peritoneal dialysis session. |
| 252 | Food & Agriculture | Convergent Bioscience | 2024 February | Haynes, Christie | Silica Nanoparticles (SNPs) derivatives that can improve plant health and vigor by creating a platform technology that can interact with other compounds to impact plant health. |
| 251 | Energy & Environment | WhirrlEnergy | 2024 February | Various: Richard James, Huan Liu | Technology for a vertical axis wind turbine that provides enhanced power output and smaller footprint compared to other vertical axis wind turbines. Makes it viable for areas where horizontal axis wind turbines are not viable. |
| 250 | Biotech & Pharmaceuticals | SyntIV | 2024 January | Herschhorn, Alon | Sells a soluble CD4 protein to researchers with expanded applications in other commercial areas including diagnostics and therapeutics for viral indications. |
| 249 | Energy & Environment | DIY Trees | 2024 January | Natural Resource Research Institute (NRRI) | Sells hybrid poplar trees, InnovaTree, directly to homeowners via mail. |
| 248 | Software & Information Technology | Flyover Country, LLC | 2024 January | Myrbo, Amy | Software development company supporting requests for data and updates to UMN's NSF funded popular Flyover Country App. |
| 247 | Software & Information Technology | Nu Compaction | 2023 December | Sun, Calvin | Nu Compaction is a software company focused on simulating the longevity of powder compaction. Numerous applications including soaps, explosives & pharmaceuticals. |
| 246 | Software & Information Technology | DecoGenomics | 2023 December | Faulk, Chris | DecoGenomics is a small business created by the researcher to respond to non-research requests to his lab related to DNA sequencing. |
| 245 | Medical Devices | Magtection | 2023 December | Wang, Jianping | A novel magnetic particle spectroscopy (MPS) diagnostic device that provides an inexpensive, portable, quantitative and rapid turnaround time to address present diagnostic challenges in human, animal health and community or herd diagnostic sampling. |
| 244 | Medical Devices | NuSonex | 2023 December | Ebbini, Emad | Dual Mode Ultrasound Array (DMUA) ultrasound to diagnose and treat myofascial pain. First indication is lower back pain with a desktop clinic system. Second indication is neck pain. |
| 243 | Medical Devices | BrainSpec | 2023 November | Oz, Gulin | MRI spectroscopy software solution compatible with the major MRI scanners to perform a virtual biopsy on a wide range of neurological disorders and traumatic brain injuries. |
| 242 | Medical Devices | PhysiAroma | 2023 October | Groenke, Beth | Advancing a medical device to help millions suffering with chronic pain. The integration of pain management techniques, novel scent delivery and AI creates a scalable solution expanding individual's ability to control their pain. |
| 240 | Engineering & Physical Science | PHOS | 2023 August | Elmer-Dixon, Margaret | PHOS is developing a method to measure plastic degradation using a topical chemical combined with AI leveraging standard visual sensors (Phones/Cameras). PHOS tech can inspect plastic coatings in infrastructure or be used in manufacturing spot checks. |
| 239 | Medical Devices | Safeguard Medical | 2023 August | Seppelt, Andi | Safeguard Medical is working to improve safety of nurses, police officers and teachers with a device that is easily deployed to subdue violent patients and/or individuals without restricting that individual's breathing or causing additional injuries. |
| 238 | Biotech & Pharmaceuticals | Impilo Therapeutics | 2023 August | Dehm, Scott | Impilo Therapeutics is a newco with a nanoparticle delivery tech. and it also has expertise in Antisense Oligonucleotides (ASO) discovery and screening. |
| 237 | Biotech & Pharmaceuticals | Kommodo Therapeutics | 2023 July | Various: Branden Moriarity, Beau Webber | Developing gene editing technology (CRISPR/CAS9) to modify T-cells to express genes of therapeutic interest(s). |
| 236 | Medical Devices | Vista Biomedical | 2023 July | Various: Joe Weber, Sandy Liu, Beth Groenke | Developing a urinary diagnostic/screen that uses your cell phone camera to interpret the test results for at home testing and screening of common conditions. |
| 235 | Biotech & Pharmaceuticals | ReBase BioTech | 2023 June | Mereddy, Venkatram | Developing small molecule compounds for the treatment of cancer. |
| 234 | Medical Devices | Faberge Fertility | 2023 June | Broberg, Dan | An In-Vitro Fertilization (IVF) Embryo Transfer Catheter that uses the embryo culture media rather than air. |
| 233 | Medical Devices | OmniKog | 2023 April | Lim, Kelvin | Cognitive neuromodulation system used to treat patients with mental health disorders. The first targeted mental health disorder indication will be treating substance abuse addiction. |
| 232 | Biotech & Pharmaceuticals | Boyan Therapeutics | 2023 April | Pang, Hongbo | Peptide-guided glucocorticoid drugs that better manage a wide variety of inflammatory conditions. |
| 231 | Engineering & Physical Science | Particle4X | 2023 April | Hong, Jiarong | Air borne particle analysis tool using a 3D imaging sensor based on digital inline holography (DIH) for measurements of size distribution, shape, concentration and other physical properties. |
| 230 | Biotech & Pharmaceuticals | Marpam Pharmaceuticals | 2023 April | Skinner, Pamela | Cellular immunotherapy to lead to durable remission of HIV in the absence of antiretroviral drugs. |
| 229 | Biotech & Pharmaceuticals | Priogen Biosciences | 2023 March | Larsen, Peter | Diagnostic company specializing in protein amplification assays for detecting prion diseases in wildlife, livestock, and humans. |
| 228 | Energy & Environment | Carba | 2023 March | Dauenhauer, Paul | Process applied to plant-based products that converts their waste to a recalcitrant solid carbon and sequester carbon dioxide via carbon underground to stabilize it for thousands of years. |
| 227 | Medical Devices | Objective Biotechnology | 2023 March | Bangalore Kodandaramaiah, Suhasa | Robotic platform for high throughput single cell gene manipulation in intact tissue that is faster and yields better results than current practices. |
| 226 | Energy & Environment | Standup Energy | 2023 February | Ellison, Chris | A technology to replace the toxic solvent NMP in battery electrode fabrication with renewable camphene. |
| 225 | Medical Devices | Granite Mountain Medical | 2023 February | Medical Device Center Fellows | A urinary catheter stabilizer that addresses severe urethra erosion due to long term catheterization. |
| 224 | Medical Devices | MR Access | 2023 February | Vaughan, Tommy | Low cost, full body MRI that is the size of and portability of a half shipping container. It uses the cloud and remote radiologists to provide MRI services in clinics and healthcare provider locations where MRI has never been possible. |
| 223 | Medical Devices | Kantika | 2023 February | Various: Gianluigi Veglia, Manu Veliparambil Subrahmanian | AI technology that optimizes MRI RF pulses by applying novel RF pulses to significantly reduces MRI scan time and improves image quality. |
| 222 | Medical Devices | Adialante | 2023 January | Garwood, Mike | MRI technology that significantly reduces hardware cost and size by eliminating the need for gradient coils, one of three basic components in MRI scanners. |
| 221 | Biotech & Pharmaceuticals | Papillon Biosciences | 2022 December | Kokkoli, Efrosini | Papillon Biosciences is a Johns Hopkins (JHU)/UMN startup using DNA nanotubes as a delivery platform for therapeutics to bind and attack glioblastoma multiforme (GBM) brain tumors. |
| 220 | Engineering & Physical Science | ANAFLASH | 2022 November | Kim, Chris | Developing semiconductor solutions for smart edge IoT devices. |
| 219 | Medical Devices | VOCxi Health | 2022 November | Medical Devices Center | Breath diagnostic system with first indication for early detection of lung cancer. |
| 218 | Biotech & Pharmaceuticals | Trekka Therapeutics | 2022 November | Wang, Chung | Developing drug delivery solutions for hard to deliver, existing therapeutics improving the formulation of compounds, peptides, proteins, and vaccines that suffer from poor stability, short in-vivo half-life, and adverse side effects. |
| 217 | Medical Devices | Alexandria BioTech | 2022 October | Selim, Ahmed | Cardiopulmonary resuscitation catheter device for interim cardiac arrest treatment between manual chest compressions and full ECMO. |
| 216 | Biotech & Pharmaceuticals | Herald Therapeutics | 2022 September | Various: David Ingbar, Tim Rich | Thyroid Hormone treatment for Acute Respiratory Distress Syndrome (ARDS). |
| 215 | Medical Devices | MAP/PATH | 2022 August | Sreevatsan, Srinand | Provides accessible, over the counter diagnostics for mycobacterium infections, including tuberculosis(TB). |
| 214 | Biotech & Pharmaceuticals | Myriel | 2022 August | Hsiao Ashe, Karen | Treatment, research and development for dementia, parkinsons and alzheimers. |
| 213 | Medical Devices | UltraHearing Technologies | 2022 July | Lim, Hubert | Hearing improvement platform with applications to treat tinnitus, hearing loss, and replace hearing aids. |
| 212 | Energy & Environment | Sustainable Water Infrastructure Group | 2022 June | Natural Resource Research Institute (NRRI) | Designs, builds, finances and operates innovative nutrient removal systems to restore and protect nutrient-impaired waters from nitrogen and phosphorus pollution. |
| 211 | Biotech & Pharmaceuticals | Myogenica | 2022 June | Various: Rita Perlingeiro, Michael Kyba | Cell therapy for generating healthy functional muscle for muscular dystrophies. |
| 210 | Energy & Environment | LoopCO2 | 2022 June | Various: Ian Tonks, Jimmy Chiu | Developing a unique monomer that will create a biodegradable polymer for use in specialty plastics. |
| 209 | Food & Agriculture | Verilytix | 2022 June | Krueger, Quinton | AI solutions for Cannabis growers. Increases yield, reduces production costs. |
| 208 | Biotech & Pharmaceuticals | Luminary Therapeutics | 2022 June | Moriarity, Branden | T-Cell solid tumor cancer therapy company focused on reducing relapse rates in CAR-T therapies. |
| 207 | Medical Devices | Rehabnetics Medical | 2022 May | Konczak, Juergen | Rehabilitation device that uses gamification and wrist motion to accelerate and improve recovery from strokes. |
| 206 | Biotech & Pharmaceuticals | Bespoke Biotherapeutics | 2022 April | Moriarity, Branden | Unlocking the vast potential of engineered B-cell therapeutics to address the physical and emotional needs of persons with cancer. |
| 205 | Energy & Environment | Aza Power | 2022 March | Northrup, Will | Reforming Ammonia to hydrogen and nitrogen for use as combustible fuel. |
| 204 | Biotech & Pharmaceuticals | Connuct | 2022 March | Mereddy, Venkatram | Small molecule cancer therapeutics. |
| 203 | Medical Devices | Adapt Design Works | 2022 March | Various: Timothy Truty, Gary Goldish, Christine Olney, Alexandra Bornstein, Andrew Hansen | Pressure mapping technology for wheelchairs helping patients reduce pressure points that can lead to reduced pressure sores. |
| 202 | Energy & Environment | SiLi-ion | 2022 March | Kortshagen, Uwe | Plasma-generated, silicon-based nanoparticles (quantum dots) applied into graphite blend to enhance storage capacity of lithium-ion batteries. |
| 201 | Medical Devices | Champaign Imaging | 2022 March | Garwood, Mike | Improvements to MRI systems that reduces impact of patient movement targeted as pediatric patients thus reducing need for repeated scans. |
| 200 | Biotech & Pharmaceuticals | Knine Biotech | 2022 February | Various: Jaime Modiano, Taylor Depauw, Ali Khammanivong | Artificial Intelligence for Early Cancer Detection in canines. |
| 199 | Software & Information Technology | Xanthos Health | 2022 January | Various: David Haynes, Pinar Karaca Mandic | The platform supports information sharing between mobile apps, EHR apps and organization apps with enhanced features like filtering, push notifications, and alerts that notify organizations and providers of patient needs. |
| 198 | Food & Agriculture | NovelSoy | 2021 December | Lorenz, Aaron | Commercialization of high-oleic soybeans. |
| 197 | Medical Devices | AxionBio | 2021 November | Ebbini, Emad | Magnetic stimulation device for non-invasive stimulation of the phrenic nerve to exercise the diaphragm thus weaning a patient off a ventilator faster. |
| 196 | Biotech & Pharmaceuticals | Unleash Therapeutics | 2021 October | Various: Michael Olin, Christopher Moertel | Use of CD200 inhibitors for canine cancers. |
| 195 | Software & Information Technology | Reflective Performance | 2021 September | Various: Stephanie Carlson, Phil Zelazo | Productivity tools to improve workforce management (recruitment, retention, development, performance) that measures and improves Executive Function (EF) — the attention-regulation skills used in goal-directed problem-solving and emotional control. |
| 194 | Software & Information Technology | TerraCover | 2021 September | Various: Ankush Khandelwal, Vipin Kumar | Physics guided machine learning for satellite imagery analysis at global scale, built on decades of University research on land cover change detection. |
| 193 | Biotech & Pharmaceuticals | Evia Bio (formerly Blue Cube) | 2021 September | Various: Allison Hubel, Kathryn Pollock | Non-DMSO cryopreservation product that increases the viability of preserved cells for future delivery to cell and gene therapy patients. |
| 192 | Biotech & Pharmaceuticals | Rancho Santa Fe Bio | 2021 September | Various: Michael Walters, Gurpreet Singh & Jon Hawkinson | Drug that slows the progression of calcification in people with aortic valve stenosis. |
| 191 | Medical Devices | Fasikl | 2021 July | Yang, Zhi | A peripheral neural interface Computer-On-a-Chip that, when paired with a neural cuff, enables new levels of neural communication both into and out of the human body potentially enabling prosthetic limbs to have human like functionality. |
| 190 | Biotech & Pharmaceuticals | iMacular Regeneration | 2021 June | Olsen, Timothy | A surgically implanted tissue support structure for regenerative medicine-based treatment approaches to macular degeneration. |
| 189 | Medical Devices | VitriStor | 2021 June | Bischof, John | Proprietary approach to significantly increasing the viability of cells in the Freezing and thawing process for liver cells. |
| 188 | Biotech & Pharmaceuticals | Diastol Therapeutics | 2021 June | Dudley, Sam | Therapy for the Treatment of Diastolic Dysfunction. |
| 187 | Food & Agriculture | Understanding Dairy Markets | 2021 June | Bozic, Marin | Service business to subscribers that monitors and publishes information related to the dairy industry. |
| 186 | Software & Information Technology | Savvy Systems | 2021 June | Hepburn, Ken | Culturally-adapted, multi-translated, and nationally adopted education solutions for family caregivers of Alzheimer’s and dementia patients. |
| 185 | Energy & Environment | Lakril Technologies | 2021 June | Dauenhauer, Paul | Process to bring sustainability to chemical production with initial focus on acrylic acid / acrylates. |
| 184 | Biotech & Pharmaceuticals | Pioneering Clinical Research | 2021 May | Sanchez, Otto | Treatment of metabolic and cardiovascular complications of peripheral arterial disease using a synthetically engineered natriuretic peptide. |
| 183 | Biotech & Pharmaceuticals | Frontline Biotechnologies | 2021 May | Abbas, Abdennour | Biological sample processing technologies, including bio-sampling, bio-separation and bioconcentration, to enable rapid and remote diagnostics. |
| 182 | Software & Information Technology | Q-Rounds | 2021 May | Various: Michael Pitt, John Sartori | Web-based inpatient virtual queue and communications platform that decreases costs and medical errors by increasing efficiency and satisfaction of the inpatient hospital rounds experience. |
| 181 | Biotech & Pharmaceuticals | Nanite | 2021 March | Reineke, Theresa | Polymer-based, nonviral systems for binding, encapsulation, and delivery of biomolecular payloads in a well-defined manner and in an efficient and low-cost manner compared to viral delivery systems. |
| 180 | Energy & Environment | Terrafore | 2021 February | Natural Resource Research Institute (NRRI) | Thermal Energy Storage (TES) for use in Concentrating Solar Thermal Power (CSP). Other non-solar energy storage applications include fossil, nuclear power plants, and industrial processes. |
| 179 | Medical Devices | Aspire Air | 2021 February | Hogan, Christopher | Portable hood that covers a patient’s head while in a hospital bed reducing the spread of infectious disease. Vents to an external filter, allows caregivers access to the patient. |
| 178 | Medical Devices | Habit Camera | 2021 February | Various: Andrew Hansen, Gary Goldish (VA/UMN) | Low-cost, wireless camera that is optimized for skin inspection and telehealth patient care. |
| 177 | Engineering & Physical Science | Intermix Performance Material | 2021 January | Bates, Frank | Technology that increases the efficiency and cost effectiveness of recycling post-consumer mixed plastic waste by producing a higher quality resultant resins that deliver a superior performance polymer alloys comprised of polypropylene and polyethylene. |
| 176 | Engineering & Physical Science | ZeroTabs | 2020 December | Various: Amrit Supriya, Trung Ha | Ergonomic standing desk. |
| 175 | Energy & Environment | UreaKnowHow | 2020 November | Wackett, Larry | Enzyme that removes biuret and triurets from urea solution and opens up new markets for urea. |
| 174 | Biotech & Pharmaceuticals | NorthStar Genomics | 2020 October | Various: Dan Garry, Mary Garry | Business will enable the creation of humanized organs in pigs including heart, skeletal tissues, vasculature and blood products. |
| 173 | Software & Information Technology | Exergi Predictive | 2020 September | Northrup, Will | Data analytics system to Improve vehicle fuel and/or electric efficiency of hybrid electric trucks used in commercial applications such as last-mile delivery and fleet services. |
| 172 | Biotech & Pharmaceuticals | EV Therapeutics | 2020 July | Subramanian, Subree | Use of Modified Extracellular Vehicles to Boost Immune Response in Colorectal Cancer. |
| 171 | Medical Devices | Owl Navigation | 2020 July | Various: Noam Harel, Guillermo Sapiro | Brain maps for accurate location and targeting for deep brain stimulation used with patients for non-Parkinson’s indications. |
| 170 | Biotech & Pharmaceuticals | RoundtableRx | 2020 June | College of Pharmacy | Non-profit providing logistics management to repurpose low risk drugs yet valuable drugs to low income / high need people where the drugs would typically get disposed of. |
| 169 | Software & Information Technology | Speech & Language Collaborative | 2020 June | Clinical and Translational Science Institute | Unique, child-friendly, software tools that are used with autistic children to help them adapt to changing activities and environment. |
| 168 | Software & Information Technology | Track AI | 2020 May | Unver, Baris | Leverages artificial intelligence to enhance public safety by transforming surveillance into actionable insights. Focused on crime prevention and detection, it empowers law enforcement to analyze video and data efficiently, increase accuracy, and reduce human error and reliance for faster, data-driven decisions. |
| 167 | Software & Information Technology | Training+U | 2020 February | Cline, Heather | Training tools for parent involvement in family training for self-reflection and dialog. |
| 166 | Biotech & Pharmaceuticals | Catamaran Bio | 2020 February | Various: Brandon Moriarity, Beau Webber | Company will focus on delivering NK Cell therapy for whole organ cancer treatment. |
| 165 | Medical Devices | 2nd Wave | 2020 February | Lim, Hubert | Coordinated ultrasound and electrical stimulation of spleen to reduce inflammation and treat autoimmune disorders. |
| 164 | Biotech & Pharmaceuticals | Sarcio Technologies (formerly Superior Organoid Technologies) | 2020 February | Various: Tim O’Brian, Beth Lindborg, Amanda Vegoe | The Company will provide human chondrocytes to patients with cartilage injuries and osteoarthritis to repair damaged cartilage and restore normal function and mobility. |
| 163 | Biotech & Pharmaceuticals | Bright Star Therapeutics | 2020 January | Various: Joshua Hou MD, Peter Bedard Ph.D., Ching Yuan Ph.D. | Developing a therapeutic treatment for a cause of retinal blindness, Limbal Stem Cell Deficiency. |
| 162 | Engineering & Physical Science | Counterflow Technologies | 2020 January | Various: Alison Hoxie, Paul Strykowski, and Vinod Srinivasan | Spray nozzles for liquids which use less air, pressure and energy to apply a range of low and high viscosity liquids. These nozzles can be retrofitted to most, if not all, existing spray installations. |
| 161 | Food & Agriculture | Nutricepts LLC | 2020 January | Various: Lloyd Metzger, Donald A. Grindstaff | Provides unique, value-added food ingredients such as an additive to improve cheese taste, quality and consistency. |
| 160 | Medical Devices | Stim Sherpa | 2019 December | Various: David Darrow, Logan Grado, Andrew Lamperski, Tay Netoff, Bryan Moore | Software that provides individualized, optimum device performance using a Bayesian optimization algorithm that learns patient preference for spinal cord stimulators in paraplegics and for deep brain stimulators (DBS) for epileptic patients. |
| 159 | Engineering & Physical Science | Grip Molecular Technologies | 2019 December | Various: Steve Koester, Sang-Hyun Oh, Mike McAlpine | A graphene-based sensor that enables lower cost, higher performance testing for infectious disease diagnostics. |
| 158 | Engineering & Physical Science | Carpe Diem | 2019 November | Various: Lorraine Francis, Dan Frisbie | Self-aligning roll-to-roll nano imprint lithography and atomic layer deposition systems and technologies used to make flexible hybrid electronics, optics and functional surfaces. |
| 157 | Software & Information Technology | Nfluence Analytics | 2019 November | Srivastava, Jaideep | AI software algorithms that aid digital marketing firms in targeting high value customers. |
| 156 | Medical Devices | Aperios Technologies | 2019 October | Yang, Zhi | Digital-to-Analog solution enabling a neuromodulation therapy to control pain. |
| 155 | Biotech & Pharmaceuticals | Austin Biosciences | 2019 August | Yang, Da-Qing | Minimally invasive, safe, and economic diagnostic blood test for high-risk women with pre-invasive or metastatic breast cancer. |
| 154 | Food & Agriculture | Insight Sensing | 2019 July | Various: Carl Rosen, Tyler Nigon | Precision agriculture software for nutrient management enabling remote sensing to predict crop nitrogen status. Insight Sensing was acquired by Sentera in 2021. |
| 153 | Biotech & Pharmaceuticals | NovoClade | 2019 July | Various: Maciej Maselko, Michael Smanski | Developing state of the art genetic biocontrol solutions for mosquitoes and agricultural insect pests. |
| 152 | Medical Devices | Reprise Biomedical | 2019 July | Various: Doris A Taylor, Harold Ott | Develops, manufactures and sells medical devices based on perfusion decellularization technology that supports cellular integration with initial focus on soft tissue repair for reinforcement in plastic and reconstructive surgery and wound care. |
| 151 | Energy & Environment | Darcy Solutions | 2019 June | Randolph, Jimmy | Novel heat exchanger that uses the flow of the underground water streams to increase efficiency of the residential and commercial heat pump. Works with standard water well drilling. |
| 150 | Medical Devices | Hybridge Medical | 2019 June | 2018 Medical Device Center Fellows | Tool for taking biopsy samples from the lung. |
| 149 | Biotech & Pharmaceuticals | Anatomic (formerly Anatomi) | 2019 May | Various: James Dutton, Patrick Walsh | Technology that allows for rapid development of neuronal cells from stem cells thus facilitating faster drug development. |
| 148 | Food & Agriculture | Jord BioScience | 2019 April | Kinkel, Linda | Biological plant control mechanism that promotes increase crop yields with a mixture of bacteria that can be optimized for a specific crop and for a specific set of physical and environmental conditions. |
| 147 | Biotech & Pharmaceuticals | Stryke Club | 2019 April | Mcguinness, Sheilagh | Grooming/acne skin care line for boys. |
| 146 | Software & Information Technology | Belalcazar Consulting | 2019 April | Various: Robert Patterson, Li Wang, Andres Belalcazar, Fei Yang | Software measuring thoracic impedance that provides information on fluid load in patients with heart failure. |
| 145 | Medical Devices | Invisian | 2019 February | Various: Laura-Lee Brown, Alan Johnson, Samuel Levine, Christopher Roffas | An orthodontic device system for simplified jaw fixation. |
| 144 | Medical Devices | Interventional Pulmonary Solutions | 2019 February | Various: Felix Landaeta, Roy Cho, Doug Devens | Medical device for placement, repositioning or removal of central airway stent. |
| 143 | Software & Information Technology | Sciamble, Inc | 2019 January | Various: Ned Mohan, Siddharth Raju | Simulation software with hardware integration for real-time controllers. To be used in high school and undergraduate programs. |
| 142 | Medical Devices | BGK, LLC | 2019 January | Various: Matt Kudek, MD 2018 Medical Device Center Fellow | lntraoral device offers targeted drug delivery when placed in the mouth between the upper and lower teeth. |
| 141 | Medical Devices | Sollievo Pharmaceuticals | 2018 December | Various: Ronald Siegel, James Cloyd | Novel compound and proprietary intranasal drug delivery device for treating epilepsy and other indications. |
| 140 | Energy & Environment | Geofinancial Analytics | 2018 December | Institute on the Environment Team | Satellite image analysis that delivers transparency on fugitive methane emissions from super emitters to aid investment professionals in near real time. |
| 139 | Medical Devices | Aurora Concussion Therapy Systems | 2018 December | Various: Shannon Smith, Kevin Goodwin, Medical Device Center Fellows | Technology to speed concussion recovery using infrared light therapy. |
| 138 | Energy & Environment | Plasma Blue (Plasma Technology Holdings) | 2018 November | Various: Shaobo Deng, Forrest lsuno | Process that uses a plasma energy field that reacts to soybean oil which is the main component of this fuel to produce biodiesel. |
| 137 | Software & Information Technology | eaterpad | 2018 September | Nutrition Coordination Center | eaterpad is an app that will help you better understand your eating habits by using nutritional data from the UMN Nutrition Coordination Center. |
| 136 | Biotech & Pharmaceuticals | Stratix | 2018 September | Salomon, Christine | Technology that enables researchers to grow high quality biofilms with consistency and reproducibility that better model how biofilms exist in nature and in vivo. |
| 135 | Medical Devices | RetiSpec Inc | 2018 September | Vince, Robert | Alzheimer Diagnostic that uses images of the eye and software to analyze the image to provide a very early detection of the onset of Alzheimer's at a stage where intervention may reduce progression. |
| 134 | Medical Devices | Cerovations | 2018 August | 2017 Medical Device Center Fellows | Implanted, redundant drain line from the brain to the abdomen to improve the drainage of fluid off the brain after trauma. |
| 133 | Biotech & Pharmaceuticals | Cancer Therapeutics Laboratories | 2018 July | Various: John Ohlfest, Peisheng Hu (USC), Alan Epstein (USC) | Cancer therapy focused on animals with first application in canines. |
| 132 | Energy & Environment | Claros Technologies | 2018 June | Abbas, Abdennour | Compound-based nano technology water filtration solution for various water filtering and water contaminate applications. |
| 131 | Biotech & Pharmaceuticals | Salspera Therapeutics | 2018 June | Various: Daniel Saltzman, Janet Schottel | Multiple engineered and constructed Salmonella that express and secrete various immunomodulating proteins that have significant anti-tumor cancer fighting effects. |
| 130 | Software & Information Technology | Flyover Country, Inc. | 2018 June | Various: Amy Myrbo, Shane Loeffler | Software application for consumers who fly that gives them interesting information on geographic points of interest as they fly over the location. |
| 129 | Biotech & Pharmaceuticals | Qlaris Bio (CalypsoQ) | 2018 June | Various: Peter Dosa, Michael Frautsch (Mayo) | Compound that is used with current Glaucoma therapy treatment to significantly enhance the therapeutic performance reducing the number of treatments needed. |
| 128 | Medical Devices | Simagine Medical | 2018 June | Various: Robert Sweet, Troy Reihsen | Tools and systems for simulating healthcare procedures and treatments that improves the delivery of procedure reducing errors and improve efficiency. |
| 127 | Medical Devices | Prescix Medical | 2018 May | Devens, Doug (MDC Fellow) | New process/technique that cleans and sterilizes flexible ureteroscopes reducing healthcare risk associated with contamination including debris, residue, and bacteria. |
| 126 | Energy & Environment | BKB Floral | 2018 April | Hillmyer, Marc | Renewable polymer to produce a green material that can be used in the florist industry replacing the material used to mount stemmed plants in vases and retain moisture for display. Company now operates under the name Phoam Labs. |
| 125 | Software & Information Technology | Dridam | 2018 April | Candler, Graham | Enhancement to US3D software models enabling scalable and more flexible identification of high-speed aerodynamics and aerodynamic heating problems faster and more accurate. |
| 124 | Software & Information Technology | Daynamica | 2018 March | Fan, Yingling | Smartphone application for capturing travel data and user experience for data gathering and research applications in transportation and logistics. |
| 123 | Software & Information Technology | PeopleStat | 2018 March | Siegel, Ron | Collects and analyzes anonymized data streams and couples with machine learning to provide feedback to people who are either pre-diabetic or actively diabetic so that they can make appropriate lifestyle changes. |
| 122 | Food & Agriculture | Planetarians | 2017 December | CFANS Food Science and Nutrition | Planetarians makes plant-based chips from up-cycled sunflower oilcake meal. Planetarians shows that repurposing oilcakes from an animal into the human food can feed up to 1.5B extra people without growing extra crops. |
| 121 | Medical Devices | Yonder | 2017 December | 2017 Medical Device Center Fellows | An application that runs on a tablet device for children to use before they visit the dentist with the objective of reducing the anxiety brought on by the pending visit. |
| 120 | Medical Devices | Vascudyne, Inc | 2017 July | Various: Bob Tranquillo, Zeeshan Syedain, Lee Meier | Surgically implantable heart valves and arteries made from decellularized tissue tubes. These assimilate to the cardiovascular structure and grow with the patient - ideal for children needing heart repairs that can grow with them. |
| 119 | Software & Information Technology | Farm Vision Tech, Inc | 2017 June | Various: Volkan Isler, Patrick Plonski | Imaging software that works with existing drones and their imaging technology to provide farmers a view on crops. Aids on prep and plans for harvesting. |
| 118 | Engineering & Physical Science | MerTron, LLC | 2017 June | Various: Sandra Myers, David Bowles, Jim Marti | A technology that captures mercury when a human body is cremated, thus eliminating any mercury escaping into the atmosphere. |
| 117 | Software & Information Technology | Turing Tumble, LLC | 2017 May | Various: Paul Boswell, Jiaoyang Li | An interactive , educational board game that when complete, simulates the way computers work. |
| 116 | Biotech & Pharmaceuticals | CoreBiome, Inc. | 2017 May | Various: Dan Knights, Kenny Beckman, Daryl Gohl | Service company that provides expert analysis and accurate genomic profiles of microbial communities (microbiomes) to customers in pharmaceuticals, agriculture, and academic research. Corebiome was acquired by Orasure in January 2019. |
| 115 | Energy & Environment | enVerde, LLC | 2017 April | Various: Lanny Schmid, Paul Dauenhauer | Converts various solid biomass components to syngas, an important chemical intermediate used to make synthetic natural gas, ammonia, methanol and other chemicals. |
| 114 | Engineering & Physical Science | Aerem, LLC | 2017 April | Various: David Pui, Qisheng Ou, Qingfeng Cao | Developing an advanced gas particulate filter system for vehicles to address stringent emissions requirements in China. |
| 113 | Engineering & Physical Science | House 3 (Carponentry, LLC) | 2017 April | Donahue, Patrick | Designs, processes and equipment to enable the building of distributive production capacity for a unique residential housing product for the single family detached market. |
| 112 | Software & Information Technology | VirtusAero, LLC | 2017 April | Various: Graham Candler, Heath Johnson, Pramod Subbareddy, Loannis Nompelis, Travis Drayna | Provides support for corporate, government, and academic users of US3D. The US3D software models heat flows at supersonic flight speeds for research, military, and commercial applications. |
| 111 | Biotech & Pharmaceuticals | OX2 Therapeutics, Inc. | 2017 April | Various: Michael Olin, Chris Moertel, John Ohlfest, Walter Low | Develop a multifaceted platform technology that is a highly efficacious treatment against solid tumor cancers. Initial target is brain tumors. |
| 110 | Energy & Environment | Resynergi | 2017 February | Ruan, Roger | Resynergi converts waste plastic to oil using microwave pyrolysis technology. |
| 109 | Energy & Environment | Sironix Renewables | 2017 February | Various: Paul Dauenhauer, Christoph Krumm, Christine Joseph, Dae Sung Park, Dionisos Vlachos, Raul Lobo, Muara Koehle | Combines plant-based ingredients into functional chemicals that will change the way in which we make laundry detergents, produce safer agricultural pesticides, and even improve how oil spills are cleaned up. |
| 108 | Biotech & Pharmaceuticals | General Probiotics | 2017 January | Various: Yiannis Kaznessis, K. Volzing, J. Del Pino, G. Dunny, B. Forcus, K. Geldart | Producer of probiotics for farm animals that express antimicrobial peptides (AMPs) only if and when an gastrointestinal infections occurs from dangerous pathogens such as E. coli and Salmonella. The se probiotic bacteria withstand the harsh environment of the GI tract. |
| 107 | Medical Devices | Cell Therapy Solutions | 2017 January | Hubel, Allison | Device that reduces cell loss, processing time, and labor costs for multiple types of cryopreserved cells (e.g., stem cells and blood cells). |
| 106 | Software & Information Technology | R5VR | 2016 December | Anderson, Lee | Software interfaces and service that take architectural drawings and create a VR experience so clients can VR the space they are going to build. |
| 105 | Medical Devices | Soundly | 2016 December | Various: Brian Krohn, Adam Black, Medical Devices Center fellows | Soundly is a simple, non-invasive way to reduce snoring using an app on your smartphone. Backed by evidence-based sleep medicine research, the app engages the user in fun snore-reducing exercises. |
| 104 | Software & Information Technology | LEIF (Sustainalytics) | 2016 November | Various: Rylie Pelton, Andrew Fang, Mark Reiner | Assists cities and communities in the assessment of environmental and social impact of infrastructure projects. Services include: environmental footprinting, sustainability action analysis and data trend visualizations. |
| 103 | Energy & Environment | Cleanair-CARE LLP | 2016 September | Various: Charles Lo, David Pui, Tom Kuehn, Sheng-Chieh Che | Renewable, energy efficient method to clean large amounts of outside air specifically targeting urban air in Chinese cities such as Beijing. Uses an adaptive spray array to remove particulate matter from the air. |
| 102 | Engineering & Physical Science | Ensor, Inc. | 2016 July | Kortshagen, Uwe | Battery chemistry and manufacturing process for a silicon dominant based anode that will triple the anode energy density and provide minimal loss in capacity retention. |
| 101 | Software & Information Technology | Modus (BSTM) | 2016 June | Carlson, Lockwood | Delivers "Technology Foresight" — a product for enterprise companies that enables forecasting, strategic planning, R&D strategy, and decision-making of their technology roadmaps. |
| 100 | Food & Agriculture | Good Libations | 2016 May | Peterson, Devin | Food additive that addresses problems with harsh taste for various consumable liquids. Initial focus on dark alcohols. |
| 099 | Medical Devices | Digital Design Studios | 2016 April | Lutfy, Patricia | Orthotic targeted at people who suffer from bunions, aiding in comfort and facilitating an active lifestyle. |
| 098 | Engineering & Physical Science | Bolder Flight Systems | 2016 March | Various: Brian Taylor, Chris Regan | Company provides software and hardware for a variety of Drone navigation products and systems. |
| 097 | Biotech & Pharmaceuticals | Antibiotic Alternatives | 2016 March | Herzberg, Mark | Novel antimicrobial agents that thwart infection by augmenting the production of naturally occurring antimicrobial proteins in mucosal epithelial cells. |
| 096 | Biotech & Pharmaceuticals | Discovery Genomics | 2016 March | Hackett, Perry | Therapeutic gene(s) using Sleeping Beauty technology for patients that lack a functioning copy of the gene. Discovery Genomics was acquired by Immusoft in March 2016. |
| 095 | Engineering & Physical Science | Advanced Road Patch | 2016 March | Zanko, Lawrence | Application of magnetite (taconite) for use in material for road repair. |
| 094 | Energy & Environment | Valerian Materials | 2016 February | Various: Marc Hillmyer, Frank Bates, Kechun Zhang | Monomer and polymer components for high performance, biodegradable plastics from renewable, green feedstocks. |
| 093 | Biotech & Pharmaceuticals | B-MoGen Biotechnologies | 2016 February | Various: David Largaespada, Branden Moriarity, Robert Klink, Perry Hackett | Tools and proprietary methods that enable the discovery of novel treatments by creating engineered cells for research and therapeutic applications. B-MoGen was acquired by Bio-Techne Corporation in June 2019. |
| 092 | Software & Information Technology | ProValens | 2016 January | Gaugler, Joe | Provides a shared database of resources to caregivers to share with patients that provides relevant information curated by the caregiver. |
| 091 | Biotech & Pharmaceuticals | Photonic Pharma | 2015 December | Various: Dave Thomas, Razvan Cornea | Compound screening for potential drug development that enables visualize of cell activity for various targets of small molecule compounds. |
| 090 | Medical Devices | EmboMedics Gel Therapies | 2015 December | Golzarian, Jafar | Natural resorbable gel product that is used to deliver therapeutic drugs into the body for various treatments, including pain. EmboMedics was acquired by QX Medical in May 2019. |
| 089 | Energy & Environment | ThermChem | 2015 October | Various: Steven Heilmann, Kenneth Valentas | Energy efficient method for reducing wastewater sludge from municipal and agricultural sewage wastes and recovering lipids, phosphorus and nitrogen. |
| 088 | Engineering & Physical Science | Innotronics | 2015 October | Rajamani, Rajesh | Engineered sensing solutions for non-contacting position measurement. |
| 087 | Software & Information Technology | UpTern | 2015 August | Taylor, Brian | B2B aerial inspections and data analytics of large infrastructure (pipelines, transmission lines, rivers, roads, and railways. |
| 086 | Biotech & Pharmaceuticals | Tmunity | 2015 August | Various: Karl June (U-Penn), Bruce Blazer | Next gen immunotherapies from novel T Cell Receptor engineered T cells, regulatory T cells and universal engineered T cell platforms for cancer, infectious diseases and autoimmune diseases therapeutics. |
| 085 | Biotech & Pharmaceuticals | Blue Therapeutics | 2015 August | Various: Phil Portoghese, Ajay Yekkirala | Novel small molecule with greater pain killing potency than morphine and no abuse potential. |
| 084 | Biotech & Pharmaceuticals | Flora Therapeutics | 2015 June | Knights, Dan | Targeting gastrointestinal and metabolic diseases using bacteria as therapeutics. |
| 083 | Software & Information Technology | Andamio Games | 2015 June | Dubinsky, Janet | Interactive game-like approach to teaching neuroscience and mental health concepts. |
| 082 | Medical Devices | Stimdia (Andarta) Medical | 2015 April | Various: James Krocak, Jesus Cabrera, John Ballard | Non-invasive lung pacing device that reduces the time a patient uses a ventilator and saves significant costs. |
| 081 | Software & Information Technology | Target Genomics | 2015 April | Van Ness, Brian | Resource database, a decision support system and services for healthcare providers and patients on use of genomics. |
| 080 | Software & Information Technology | FastBridge Learning | 2015 March | Christ, Ted | Automated K-12 assessment tools for student screening, progress monitoring, and program evaluation. Fastbridge was acquired by Illuminate Education, a leading provider of education technology for grades K–12, in June 2019. |
| 079 | Software & Information Technology | Flipgrid (formerly Vidku) | 2015 February | Miller, Charlie | Platform allowing individuals to engage in rich, video-based dialogues with others organized around topics and questions. Flipgrid was acquired by Microsoft In June 2018. |
| 078 | Biotech & Pharmaceuticals | Tychon Biosciences | 2015 February | Wagner, Carston | Platform therapeutic focused on cancer treatment using chemical synthesis, custom nanomaterials and complex protein structures. |
| 077 | Food & Agriculture | Carp Solutions | 2015 February | Bajer, Pzemyslaw | Field sampling with analytics to develop sustainable management strategies for invasive fish such as carp. |
| 076 | Engineering & Physical Science | Adama Materials | 2015 January | Various: Chris Macosko, Andreas Stein | Improves the properties of resin and fiber composites, such as epoxy/carbon fiber and polyester/fiberglass, at very low cost. |
| 075 | Biotech & Pharmaceuticals | ApoGen BioTech | 2014 October | Various: Reuben Harris, Dan Harki | Delivering a new class of therapeutics, focused on APOBECs, targeting drivers of cancer genomic mutation. |
| 074 | Software & Information Technology | Early Movement Monitoring Assessment (EMMA) | 2014 September | Leitschuh, Carol | Individual Growth Development Indicators (IGDIs) for infants monitoring early movement. |
| 073 | Biotech & Pharmaceuticals | Kuality Herbceutics | 2014 September | Xing, Chengguo | Cancer therapy developed from Kava plant compound extracts. |
| 072 | Biotech & Pharmaceuticals | Bioactive Regenerative Therapeutics | 2014 August | O'Brien, Timothy | Biomimetic 3D cell culture matrix designed to support and enhance cell culture assays. |
| 071 | Software & Information Technology | Reflection Sciences | 2014 August | Various: Stephanie Carlson, Phil Zelazo | A method to test a child's ability to concentrate on a task. |
| 070 | Software & Information Technology | PSI (STA) | 2014 August | Various: Shyam Boriah, Vipin Kumar, Karsten Steinhaeuser | Satellite image analysis algorithm to detect changes in resources (forest, crops, water, urbanization). |
| 069 | Medical Devices | Blossom Medical | 2014 July | Medical Device Fellows 2012 | Neonatal medical device that cradles and supports infants during early stage of life. |
| 068 | Engineering & Physical Science | Niron Magnetics | 2014 June | Wang, Jian-Ping | New material and process to fabricate permanent magnets, eliminating the need for rare earth elements. |
| 067 | Engineering & Physical Science | Bennett Autogas Systems | 2014 June | Bennett, David | Fuel tank that is lower cost and has reduced maintenance for liquid petroleum fueled vehicles. |
| 066 | Medical Devices | MesoFlow | 2014 May | Hubel, Allison | Device that reduces cell loss, processing time and labor costs for multiple types of cryopreserved cells (e.g., stem cells and blood cells). |
| 065 | Software & Information Technology | Efficient Windows Collaborative | 2014 May | Various: Kerry Haglund, John Carmody | Website providing unbiased information on the benefits of energy-efficient windows, descriptions of how they work, and recommendations for their selection and use. Efficient Windows Collaborative was acquired by NFRC. |
| 064 | Medical Devices | Minnscan | 2014 May | Various: Michael Garwood, Donald Nixdorf | Advanced imaging system for using MRI in dental applications. |
| 063 | Biotech & Pharmaceuticals | ADC BioMed | 2014 May | Chen, Wei | Novel diagnostics and therapeutics to prevent and treat cancer, autoimmune diseases and infectious diseases. |
| 062 | Software & Information Technology | Treatment Global | 2014 May | Peterson, Kevin | Multi-disciplinary telehealth approach that provides chronic disease and health and wellness management without the need for a clinic visit. |
| 061 | Medical Devices | Vigilant Diagnostics | 2014 April | Bischof, John | Lateral flow assay system (diagnostic) that improves sensitivity of standard lateral flow assays by 10 to 100 times. |
| 060 | Medical Devices | Zepto Life Technology | 2014 March | Wang, Jian-Ping | Animal and human diagnostic solution that is accurate and highly sensitive for central lab, clinic, and point-of-care applications. |
| 059 | Energy & Environment | Minnepura | 2013 October | Various: Al Aksan, Larry Wackett, Michael Sadowsky | Encapsulation of biomaterial that provides an effective, low cost treatment solution to customers who need to remove hydrocarbons and chemicals from water. |
| 058 | Software & Information Technology | CVC Heartsavers | 2013 October | Cohn, Jay | Diagnostic that provides earlier intervention and treatment for cardiovascular disease. |
| 057 | Energy & Environment | NH3 Strategies | 2013 October | Ruan, Roger | Process for producing ammonia fertilizer with water and air that can be implemented close to farmers. |
| 056 | Software & Information Technology | InformeDesign | 2013 October | Various: Caren Martin, Denise Guerin | Searchable database that facilitates designers’ use of current, research-based information as a decision-making tool. |
| 055 | Software & Information Technology | Surgical Information Sciences | 2013 October | Various: Noam Harel, Guillermo Sapiro | Brain maps for accurate location and targeting for deep brain stimulation used with patients who have Parkinson’s disease. |
| 054 | Biotech & Pharmaceuticals | CURx Pharmaceuticals | 2013 August | Cloyd, James | Intravenous and intramuscular injection treatments for seizures in hospitalized epilepsy patients that can replace oral medications. |
| 053 | Biotech & Pharmaceuticals | ID Genomics | 2013 June | Johnson, James | Rapid assessment of virulent bacteria for potential organ failure in urgent care settings. |
| 052 | Software & Information Technology | Medjules (Synaptic Design) | 2013 June | 2013 Mechanical Design Class | Surgical training platforms that provide quantifiable feedback for medical students and practicing physicians. |
| 051 | Medical Devices | ReMinD Technologies | 2013 June | 2012 Medical Device Fellows | Developing, manufacturing and marketing consumer technologies to help patients and caregivers ensure medication adherence. |
| 050 | Software & Information Technology | Applied Informatic Solutions | 2013 June | Various: Jason Nikas, Walter Low | Informatics tools to assist with the identification of high-value biomarkers. |
| 049 | Food & Agriculture | Veterinary Diagnostics and Therapeutics | 2013 May | Conzemius, Michael | Genetic test that assesses risk for rupture of the cranial cruciate ligament in dogs. |
| 048 | Software & Information Technology | Evidentia Health | 2013 April | Steinberger, Dan | Evidence-based clinical decision support tools for radiologists at the point of care. |
| 047 | Food & Agriculture | NovaMela | 2013 April | Various: James Luby, David Bedford | Umbrella entity for leading apple companies in Italy that cultivate and sell promising new apple varieties including SweeTango. |
| 046 | Medical Devices | EmboMedics ResoSpheres | 2013 April | Golzarian, Jafar | Natural, resorbable polymer bead used to cut off blood supply to tumor/cancer cells in the body. EmboMedics was acquired by QX Medical in May 2019. |
| 045 | Medical Devices | Universal Magnetic Systems | 2013 March | Wang, Jian-Ping | Superior, high moment magnetic nanoparticles for disease detection and diagnostic target separation. |
| 044 | Medical Devices | FocusStart | 2013 February | Rajamani, Rajesh | Handheld probe that measures tension in soft tissues, such as tendons and ligaments, during invasive orthopedic surgery. |
| 043 | Energy & Environment | Ascenix Biotechnologies | 2013 January | Zhang, Kechun | Process to take sugar-based feedstocks and produce synthetic chemicals for multiple uses including production of high value plastics. |
| 042 | Medical Devices | Andas | 2012 December | Koester, Steven | Technology that conveniently communicates accurate level of intoxication via breath analysis through smart phones. |
| 041 | Food & Agriculture | The Actives Factory | 2012 October | Krasutsky, Pavel | Natural anti-inflammatory compound for the cosmetics, dietary supplements and pharmaceuticals industries. |
| 040 | Biotech & Pharmaceuticals | GY Biomedical, LLC | 2012 July | Gourley, Glenn | Non-invasive, cost-effective diagnostic and monitoring test for an inflammatory disease of the esophagus. |
| 039 | Software & Information Technology | Omicron Health Systems | 2012 June | Peterson, Kevin | Technology that helps clinicians facilitate randomized controlled trials and translates research into clinical practice. |
| 038 | Biotech & Pharmaceuticals | Epitopoietic Research Corporation (ERC) | 2012 April | Various: John Ohlfest, Walter Low | Vaccine that engages the immune system to treat glioblastoma brain cancers. |
| 037 | Biotech & Pharmaceuticals | Crestovo (formerly CIPAC, now Finch Therapeautics) | 2012 March | Various: Michael Sadowsky, Alexander Khoruts, Matt Hamilton, Alexa Weingarden | Finch is a clinical-stage microbiome therapeutics company dedicated to developing novel live microbial therapies to treat diseases such as C. difficile via microbiota transplantation. Originally licensed to CIPAC LLC who merged with Crestovo LLC in 2015, and Crestovo merged with Finch Therapeutics in 2017. |
| 036 | Software & Information Technology | Early Learning Labs | 2012 March | Various: Scott McConnell, Alisha Wackerle-Holman | Assessments and services to help parents and early child-care providers develop “kindergarten-ready” children. myIGDIs was acquired by Renaissance in April 2019. |
| 035 | Energy & Environment | TerreCOH (formerly Heat Mining Company) | 2012 March | Saar, Martin | Uses sequestered carbon dioxide to extract geothermal energy from the earth that is used to generate electricity. |
| 034 | Energy & Environment | Argilex Technologies Corp | 2012 March | Tsapatsis, Michael | Develops a membrane technology for separation processes such as those in the petroleum refining, chemicals, and biofuels industries. |
| 033 | Software & Information Technology | VitalSims | 2011 December | Various: Paul Johnson, George Biltz | Enables the observation, analysis, and improvement of physician decision making in a simulated practice setting. |
| 032 | Biotech & Pharmaceuticals | Vytacera Pharma | 2011 December | Various: Bob Vince, Steve Patterson, Herb Nagasawa | Develops technology for the prevention and treatment of cyanide poisoning. |
| 031 | Software & Information Technology | Drive Power | 2011 December | Various: Max Donath, Craig Shankwitz, Alec Gorjestani | Develops unique products that leverage emerging measurement technologies and predictive analytics to enable people to make more informed driving decisions. |
| 030 | Engineering & Physical Science | SMART Signal Technologies | 2011 October | Liu, Henry | Offers a hardware and software solution that can be used to reduce traffic congestion on major signalized arterial highways. |
| 029 | Biotech & Pharmaceuticals | Ariel Pharmaceuticals | 2011 October | Various: Matt Andrews, Les Drewes, Greg Beilman | Develops a treatment for death due to blood loss from trauma. |
| 028 | Energy & Environment | cycleWood Solutions | 2011 September | Sarkanen, Simo | Creates low-cost biodegradable and compostable bags. |
| 027 | Software & Information Technology | Ninja Metrics | 2011 June | Srivastava, Jaideep | Online social networking and gaming analytics, predicting user behavior. |
| 026 | Medical Devices | Aria CV | 2011 May | Second-year Medical Device Fellows | Medical device to treat pulmonary hypertension. |
| 025 | Biotech & Pharmaceuticals | Minneamrita Therapeutics | 2011 February | Various: Gunda Georg, Ashok Saluja | Drug for cancerous pancreatic tumors. |
| 024 | Engineering & Physical Science | Upstream Technologies | 2011 February | Gulliver, John | Sediment control in stormwater systems. |
| 023 | Biotech & Pharmaceuticals | Calyxt (formerly Cellectis Plant Sciences) | 2011 January | Various: Dan Voytas, Feng Zhang | Genome editing that can add and modify plant genes to create valuable organisms. Calyxt went public with an IPO in June 2017, and merged with Cibus in 2023. |
| 022 | Medical Devices | International Cardio Corp | 2010 December | Ebbini, Emad | Ablating vascular plaque utilizing high intensity focused ultrasound. |
| 021 | Engineering & Physical Science | United Science | 2010 November | Buhlmann, Phil | Reducing pollution through high accuracy measurement for chemical ions. |
| 020 | Biotech & Pharmaceuticals | Kingsbury Animal Health | 2010 October | Schlievert, Pat | Improves animal health and food safety by reducing harmful bacteria using glycerol monolaurate (GML). Merged with Hennepin Life Science. |
| 019 | Software & Information Technology | Clinical Innovation Labs (IBU) | 2010 September | Peterson, Kevin | Healthcare IT solution for clinical trial recruitment and physician quality reporting. |
| 018 | Medical Devices | XO-Thermix Medical | 2010 June | Cressman, Erik | Developing a unique airway thermoplasty device intended to become the standard of care in improving airway function for millions of patients with severe, persistent asthma. |
| 017 | Energy & Environment | Renovo Water (NewWater) | 2010 June | Various: Larry Wackett, Michael Sadowsky | Developing a new type of drinking water filter. |
| 016 | Software & Information Technology | Early Learning Labs (IBU) | 2010 May | Various: Scott McConnell, Alisha Wackerle-Holman | Assessments and services to help parents and early child-care providers develop “kindergarten-ready” children. Early Learning Labs (IBU) was acquired by myIGDIs and operated under a new license from March 2012 through April 2019 when myIGDIs was acquired by Renaissance Learning, Inc. |
| 015 | Biotech & Pharmaceuticals | NeurEndo Pharma | 2010 March | Portoghese, Phil | Early stage pharmaceutical development company focused on the evaluation and development of compounds for the treatment of obesity and pre-diabetes management. |
| 014 | Medical Devices | Miromatrix Medical | 2010 February | Taylor, Doris | Human organs for transplantation, manufactured using decellularization/recellularization technology. Miromatrix went public with an IPO in June 2021 under the symbol MIRO. |
| 013 | Software & Information Technology | Nouvant (CaSTT IBU) | 2010 February | Huebsch, Rick | Web-hosted, subscription-based, search engine optimization tool for intellectual property marketing, licensing and tech transfer. |
| 012 | Biotech & Pharmaceuticals | Hennepin Life Sciences | 2009 October | Schlievert, Pat | Antimicrobial technology to treat and prevent microbial infections. |
| 011 | Medical Devices | R8Scan | 2009 August | Srienc, Fredrich | Cytometry instruments that track and measure individual cells, providing detail into the dynamics of cellular growth. |
| 010 | Energy & Environment | BioCee | 2009 May | von Keitz, Marc | Cost-effective and environmentally sound production of clean fuels, chemicals, and water treatment by harnessing the full biocatalytic potential of microorganisms. |
| 009 | Biotech & Pharmaceuticals | Celladon | 2009 May | Cornea, Razvan | Molecular therapies for cardiovascular diseases. Celladon merged with EIGER Biopharmaceuticals in November 2015. |
| 008 | Engineering & Physical Science | Ascir | 2009 February | Talghader, Joey | Revolutionary solid state semiconductor-based gas detector capable of monitoring the presence of hazardous gases at a safe distance. |
| 007 | Biotech & Pharmaceuticals | VitalMedix | 2008 May | Andrews, Matt | Hemorrhagic shock drug that could keep patients temporarily alive even if they have suffered catastrophic blood loss. |
| 006 | Engineering & Physical Science | Rushford Hypersonic | 2008 March | Girshick, Steve | Coating technologies which are harder, denser and more fracture resistant than standard carbide coatings, used in the industrial tooling industry. |
| 005 | Medical Devices | Orasi Medical | 2007 September | Georgopoulos, Apostolos | Diagnostic tests that detect the unique disruptions in the electrical activity of the brain caused by Alzheimer’s disease to aid a physician in the early diagnosis and initiation of treatment of patients. |
| 004 | Medical Devices | Steady State Imaging | 2006 December | Garwood, Michael | Novel magnetic resonance imaging (MRI) technology. Steady State Imaging’s assets were acquired by GE Healthcare in April 2011. |
| 003 | Engineering & Physical Science | Recon Robotics | 2006 November | Papanikolopoulos, Nikolaos | Creates devices used by the US military, federal, state and local law enforcement agencies to protect their personnel, minimize collateral damage and gain immediate reconnaissance within dangerous and hostile environments. |
| 002 | Biotech & Pharmaceuticals | Macular Regeneration | 2006 July | Olsen, Timothy | Develops technologies to help with macular regeneration. |
| 001 | Software & Information Technology | Medication Management | 2006 April | Cipolle, Bob | Comprehensive, patient-centered medication therapy management services that identify and resolve drug therapy problems. Medication Management was acquired by Genoa Healthcare in July 2017. |
Biotech & Pharmaceuticals
Description | |||
|---|---|---|---|
| Exomed Diagnostics | 2025 February | Saydam, Nurten | Develops therapies for glioblastoma and meningioma. |
| Nanoli Therapeutics | 2024 November | Li, Fang | Developing nanobodies for various cancers and viral diseases. |
| KuriBio | 2024 November | Adamala, Katarzyna (Kate) | Developing liposomes with surface embedded receptors that express peptides to increase detectable cancer results in existing diagnostic tests. |
| NorthStar Cryo | 2024 November | Bischof, John | Developing methods and materials for the scaled preservation of small materials and cells for research and therapeutic purposes. |
| FKP Therapeutics | 2024 October | Prins, Kurt | Nanobody-Based Treatment for Right Ventricular Failure |
| Gavia Bio | 2024 August | Gorr, Sven-Ulrik | An anti-microbial hydrogel for treating chronic wounds, burns, and oral infections. The hydrogel directly attacks bacterial cell membranes to make them less susceptible to bacterial resistance |
| Crichton Biosciences | 2024 July | Verma, Vivek | Therapeutics for solid tumors by reversing cancer immunotherapy resistance through metabolic reprogramming |
| Itasca Therapeutics Inc | 2024 April | Various: Paul Robbins, Laura Niedernhofer, Laura Niedernhofer | Developing anti-aging therapeutics using small molecules that eliminate senescent cells to slow or reduce the aging effects. |
| CounterX Therapeutics Inc | 2024 April | Pravetoni, Marco | Vaccines and antibody therapeutics for treating opiate addiction addressing significant public health implications (e.g. fentanyl, heroine etc.) |
| 6D Biosystems | 2024 February | Panoskaltsis-Mortari, Angela | Commercializing the use of bioink and biological fibers for 3D tissue printing of in-vitro metastic testing models. |
| SyntIV | 2024 January | Herschhorn, Alon | Sells a soluble CD4 protein to researchers with expanded applications in other commercial areas including diagnostics and therapeutics for viral indications. |
| Impilo Therapeutics | 2023 August | Dehm, Scott | Impilo Therapeutics is a newco with a nanoparticle delivery tech. and it also has expertise in Antisense Oligonucleotides (ASO) discovery and screening. |
| Kommodo Therapeutics | 2023 July | Various: Branden Moriarity, Beau Webber | Developing gene editing technology (CRISPR/CAS9) to modify T-cells to express genes of therapeutic interest(s). |
| ReBase BioTech | 2023 June | Mereddy, Venkatram | Developing small molecule compounds for the treatment of cancer. |
| Marpam Pharmaceuticals | 2023 April | Skinner, Pamela | Cellular immunotherapy to lead to durable remission of HIV in the absence of antiretroviral drugs. |
| Boyan Therapeutics | 2023 April | Pang, Hongbo | Peptide-guided glucocorticoid drugs that better manage a wide variety of inflammatory conditions. |
| Priogen Biosciences | 2023 March | Larsen, Peter | Diagnostic company specializing in protein amplification assays for detecting prion diseases in wildlife, livestock, and humans. |
| Papillon Biosciences | 2022 December | Kokkoli, Efrosini | Papillon Biosciences is a Johns Hopkins (JHU)/UMN startup using DNA nanotubes as a delivery platform for therapeutics to bind and attack glioblastoma multiforme (GBM) brain tumors. |
| Trekka Therapeutics | 2022 November | Wang, Chung | Developing drug delivery solutions for hard to deliver, existing therapeutics improving the formulation of compounds, peptides, proteins, and vaccines that suffer from poor stability, short in-vivo half-life, and adverse side effects. |
| Herald Therapeutics | 2022 September | Various: David Ingbar, Tim Rich | Thyroid Hormone treatment for Acute Respiratory Distress Syndrome (ARDS). |
| Myriel | 2022 August | Hsiao Ashe, Karen | Treatment, research and development for dementia, parkinsons and alzheimers. |
| Myogenica | 2022 June | Various: Rita Perlingeiro, Michael Kyba | Cell therapy for generating healthy functional muscle for muscular dystrophies. |
| Luminary Therapeutics | 2022 June | Moriarity, Branden | T-Cell solid tumor cancer therapy company focused on reducing relapse rates in CAR-T therapies. |
| Bespoke Biotherapeutics | 2022 April | Moriarity, Branden | Unlocking the vast potential of engineered B-cell therapeutics to address the physical and emotional needs of persons with cancer. |
| Connuct | 2022 March | Mereddy, Venkatram | Small molecule cancer therapeutics. |
| Knine Biotech | 2022 February | Various: Jaime Modiano, Taylor Depauw, Ali Khammanivong | Artificial Intelligence for Early Cancer Detection in canines. |
| Unleash Therapeutics | 2021 October | Various: Michael Olin, Christopher Moertel | Use of CD200 inhibitors for canine cancers. |
| Rancho Santa Fe Bio | 2021 September | Various: Michael Walters, Gurpreet Singh & Jon Hawkinson | Drug that slows the progression of calcification in people with aortic valve stenosis. |
| Evia Bio (formerly Blue Cube) | 2021 September | Various: Allison Hubel, Kathryn Pollock | Non-DMSO cryopreservation product that increases the viability of preserved cells for future delivery to cell and gene therapy patients. |
| Diastol Therapeutics | 2021 June | Dudley, Sam | Therapy for the Treatment of Diastolic Dysfunction. |
| iMacular Regeneration | 2021 June | Olsen, Timothy | A surgically implanted tissue support structure for regenerative medicine-based treatment approaches to macular degeneration. |
| Frontline Biotechnologies | 2021 May | Abbas, Abdennour | Biological sample processing technologies, including bio-sampling, bio-separation and bioconcentration, to enable rapid and remote diagnostics. |
| Pioneering Clinical Research | 2021 May | Sanchez, Otto | Treatment of metabolic and cardiovascular complications of peripheral arterial disease using a synthetically engineered natriuretic peptide. |
| Nanite | 2021 March | Reineke, Theresa | Polymer-based, nonviral systems for binding, encapsulation, and delivery of biomolecular payloads in a well-defined manner and in an efficient and low-cost manner compared to viral delivery systems. |
| NorthStar Genomics | 2020 October | Various: Dan Garry, Mary Garry | Business will enable the creation of humanized organs in pigs including heart, skeletal tissues, vasculature and blood products. |
| EV Therapeutics | 2020 July | Subramanian, Subree | Use of Modified Extracellular Vehicles to Boost Immune Response in Colorectal Cancer. |
| RoundtableRx | 2020 June | College of Pharmacy | Non-profit providing logistics management to repurpose low risk drugs yet valuable drugs to low income / high need people where the drugs would typically get disposed of. |
| Sarcio Technologies (formerly Superior Organoid Technologies) | 2020 February | Various: Tim O’Brian, Beth Lindborg, Amanda Vegoe | The Company will provide human chondrocytes to patients with cartilage injuries and osteoarthritis to repair damaged cartilage and restore normal function and mobility. |
| Catamaran Bio | 2020 February | Various: Brandon Moriarity, Beau Webber | Company will focus on delivering NK Cell therapy for whole organ cancer treatment. |
| Bright Star Therapeutics | 2020 January | Various: Joshua Hou MD, Peter Bedard Ph.D., Ching Yuan Ph.D. | Developing a therapeutic treatment for a cause of retinal blindness, Limbal Stem Cell Deficiency. |
| Austin Biosciences | 2019 August | Yang, Da-Qing | Minimally invasive, safe, and economic diagnostic blood test for high-risk women with pre-invasive or metastatic breast cancer. |
| NovoClade | 2019 July | Various: Maciej Maselko, Michael Smanski | Developing state of the art genetic biocontrol solutions for mosquitoes and agricultural insect pests. |
| Anatomic (formerly Anatomi) | 2019 May | Various: James Dutton, Patrick Walsh | Technology that allows for rapid development of neuronal cells from stem cells thus facilitating faster drug development. |
| Stryke Club | 2019 April | Mcguinness, Sheilagh | Grooming/acne skin care line for boys. |
| Stratix | 2018 September | Salomon, Christine | Technology that enables researchers to grow high quality biofilms with consistency and reproducibility that better model how biofilms exist in nature and in vivo. |
| Cancer Therapeutics Laboratories | 2018 July | Various: John Ohlfest, Peisheng Hu (USC), Alan Epstein (USC) | Cancer therapy focused on animals with first application in canines. |
| Salspera Therapeutics | 2018 June | Various: Daniel Saltzman, Janet Schottel | Multiple engineered and constructed Salmonella that express and secrete various immunomodulating proteins that have significant anti-tumor cancer fighting effects. |
| Qlaris Bio (CalypsoQ) | 2018 June | Various: Peter Dosa, Michael Frautsch (Mayo) | Compound that is used with current Glaucoma therapy treatment to significantly enhance the therapeutic performance reducing the number of treatments needed. |
| CoreBiome, Inc. | 2017 May | Various: Dan Knights, Kenny Beckman, Daryl Gohl | Service company that provides expert analysis and accurate genomic profiles of microbial communities (microbiomes) to customers in pharmaceuticals, agriculture, and academic research. Corebiome was acquired by Orasure in January 2019. |
| OX2 Therapeutics, Inc. | 2017 April | Various: Michael Olin, Chris Moertel, John Ohlfest, Walter Low | Develop a multifaceted platform technology that is a highly efficacious treatment against solid tumor cancers. Initial target is brain tumors. |
| General Probiotics | 2017 January | Various: Yiannis Kaznessis, K. Volzing, J. Del Pino, G. Dunny, B. Forcus, K. Geldart | Producer of probiotics for farm animals that express antimicrobial peptides (AMPs) only if and when an gastrointestinal infections occurs from dangerous pathogens such as E. coli and Salmonella. The se probiotic bacteria withstand the harsh environment of the GI tract. |
| Discovery Genomics | 2016 March | Hackett, Perry | Therapeutic gene(s) using Sleeping Beauty technology for patients that lack a functioning copy of the gene. Discovery Genomics was acquired by Immusoft in March 2016. |
| Antibiotic Alternatives | 2016 March | Herzberg, Mark | Novel antimicrobial agents that thwart infection by augmenting the production of naturally occurring antimicrobial proteins in mucosal epithelial cells. |
| B-MoGen Biotechnologies | 2016 February | Various: David Largaespada, Branden Moriarity, Robert Klink, Perry Hackett | Tools and proprietary methods that enable the discovery of novel treatments by creating engineered cells for research and therapeutic applications. B-MoGen was acquired by Bio-Techne Corporation in June 2019. |
| Photonic Pharma | 2015 December | Various: Dave Thomas, Razvan Cornea | Compound screening for potential drug development that enables visualize of cell activity for various targets of small molecule compounds. |
| Blue Therapeutics | 2015 August | Various: Phil Portoghese, Ajay Yekkirala | Novel small molecule with greater pain killing potency than morphine and no abuse potential. |
| Tmunity | 2015 August | Various: Karl June (U-Penn), Bruce Blazer | Next gen immunotherapies from novel T Cell Receptor engineered T cells, regulatory T cells and universal engineered T cell platforms for cancer, infectious diseases and autoimmune diseases therapeutics. |
| Flora Therapeutics | 2015 June | Knights, Dan | Targeting gastrointestinal and metabolic diseases using bacteria as therapeutics. |
| Tychon Biosciences | 2015 February | Wagner, Carston | Platform therapeutic focused on cancer treatment using chemical synthesis, custom nanomaterials and complex protein structures. |
| ApoGen BioTech | 2014 October | Various: Reuben Harris, Dan Harki | Delivering a new class of therapeutics, focused on APOBECs, targeting drivers of cancer genomic mutation. |
| Kuality Herbceutics | 2014 September | Xing, Chengguo | Cancer therapy developed from Kava plant compound extracts. |
| Bioactive Regenerative Therapeutics | 2014 August | O'Brien, Timothy | Biomimetic 3D cell culture matrix designed to support and enhance cell culture assays. |
| ADC BioMed | 2014 May | Chen, Wei | Novel diagnostics and therapeutics to prevent and treat cancer, autoimmune diseases and infectious diseases. |
| CURx Pharmaceuticals | 2013 August | Cloyd, James | Intravenous and intramuscular injection treatments for seizures in hospitalized epilepsy patients that can replace oral medications. |
| ID Genomics | 2013 June | Johnson, James | Rapid assessment of virulent bacteria for potential organ failure in urgent care settings. |
| GY Biomedical, LLC | 2012 July | Gourley, Glenn | Non-invasive, cost-effective diagnostic and monitoring test for an inflammatory disease of the esophagus. |
| Epitopoietic Research Corporation (ERC) | 2012 April | Various: John Ohlfest, Walter Low | Vaccine that engages the immune system to treat glioblastoma brain cancers. |
| Crestovo (formerly CIPAC, now Finch Therapeautics) | 2012 March | Various: Michael Sadowsky, Alexander Khoruts, Matt Hamilton, Alexa Weingarden | Finch is a clinical-stage microbiome therapeutics company dedicated to developing novel live microbial therapies to treat diseases such as C. difficile via microbiota transplantation. Originally licensed to CIPAC LLC who merged with Crestovo LLC in 2015, and Crestovo merged with Finch Therapeutics in 2017. |
| Vytacera Pharma | 2011 December | Various: Bob Vince, Steve Patterson, Herb Nagasawa | Develops technology for the prevention and treatment of cyanide poisoning. |
| Ariel Pharmaceuticals | 2011 October | Various: Matt Andrews, Les Drewes, Greg Beilman | Develops a treatment for death due to blood loss from trauma. |
| Minneamrita Therapeutics | 2011 February | Various: Gunda Georg, Ashok Saluja | Drug for cancerous pancreatic tumors. |
| Calyxt (formerly Cellectis Plant Sciences) | 2011 January | Various: Dan Voytas, Feng Zhang | Genome editing that can add and modify plant genes to create valuable organisms. Calyxt went public with an IPO in June 2017, and merged with Cibus in 2023. |
| Kingsbury Animal Health | 2010 October | Schlievert, Pat | Improves animal health and food safety by reducing harmful bacteria using glycerol monolaurate (GML). Merged with Hennepin Life Science. |
| NeurEndo Pharma | 2010 March | Portoghese, Phil | Early stage pharmaceutical development company focused on the evaluation and development of compounds for the treatment of obesity and pre-diabetes management. |
| Hennepin Life Sciences | 2009 October | Schlievert, Pat | Antimicrobial technology to treat and prevent microbial infections. |
| Celladon | 2009 May | Cornea, Razvan | Molecular therapies for cardiovascular diseases. Celladon merged with EIGER Biopharmaceuticals in November 2015. |
| VitalMedix | 2008 May | Andrews, Matt | Hemorrhagic shock drug that could keep patients temporarily alive even if they have suffered catastrophic blood loss. |
| Macular Regeneration | 2006 July | Olsen, Timothy | Develops technologies to help with macular regeneration. |
Energy & Environment
Description | |||
|---|---|---|---|
| Waypoint Forward | 2024 March | Various: Abigail Clarke-Sather, Paulo Alves | Clothing recycling solution that shreds textiles down to the fibers so that they are able to be respooled into new thread. |
| WhirrlEnergy | 2024 February | Various: Richard James, Huan Liu | Technology for a vertical axis wind turbine that provides enhanced power output and smaller footprint compared to other vertical axis wind turbines. Makes it viable for areas where horizontal axis wind turbines are not viable. |
| DIY Trees | 2024 January | Natural Resource Research Institute (NRRI) | Sells hybrid poplar trees, InnovaTree, directly to homeowners via mail. |
| Carba | 2023 March | Dauenhauer, Paul | Process applied to plant-based products that converts their waste to a recalcitrant solid carbon and sequester carbon dioxide via carbon underground to stabilize it for thousands of years. |
| Standup Energy | 2023 February | Ellison, Chris | A technology to replace the toxic solvent NMP in battery electrode fabrication with renewable camphene. |
| LoopCO2 | 2022 June | Various: Ian Tonks, Jimmy Chiu | Developing a unique monomer that will create a biodegradable polymer for use in specialty plastics. |
| Sustainable Water Infrastructure Group | 2022 June | Natural Resource Research Institute (NRRI) | Designs, builds, finances and operates innovative nutrient removal systems to restore and protect nutrient-impaired waters from nitrogen and phosphorus pollution. |
| SiLi-ion | 2022 March | Kortshagen, Uwe | Plasma-generated, silicon-based nanoparticles (quantum dots) applied into graphite blend to enhance storage capacity of lithium-ion batteries. |
| Aza Power | 2022 March | Northrup, Will | Reforming Ammonia to hydrogen and nitrogen for use as combustible fuel. |
| Lakril Technologies | 2021 June | Dauenhauer, Paul | Process to bring sustainability to chemical production with initial focus on acrylic acid / acrylates. |
| Terrafore | 2021 February | Natural Resource Research Institute (NRRI) | Thermal Energy Storage (TES) for use in Concentrating Solar Thermal Power (CSP). Other non-solar energy storage applications include fossil, nuclear power plants, and industrial processes. |
| UreaKnowHow | 2020 November | Wackett, Larry | Enzyme that removes biuret and triurets from urea solution and opens up new markets for urea. |
| Darcy Solutions | 2019 June | Randolph, Jimmy | Novel heat exchanger that uses the flow of the underground water streams to increase efficiency of the residential and commercial heat pump. Works with standard water well drilling. |
| Geofinancial Analytics | 2018 December | Institute on the Environment Team | Satellite image analysis that delivers transparency on fugitive methane emissions from super emitters to aid investment professionals in near real time. |
| Plasma Blue (Plasma Technology Holdings) | 2018 November | Various: Shaobo Deng, Forrest lsuno | Process that uses a plasma energy field that reacts to soybean oil which is the main component of this fuel to produce biodiesel. |
| Claros Technologies | 2018 June | Abbas, Abdennour | Compound-based nano technology water filtration solution for various water filtering and water contaminate applications. |
| BKB Floral | 2018 April | Hillmyer, Marc | Renewable polymer to produce a green material that can be used in the florist industry replacing the material used to mount stemmed plants in vases and retain moisture for display. Company now operates under the name Phoam Labs. |
| enVerde, LLC | 2017 April | Various: Lanny Schmid, Paul Dauenhauer | Converts various solid biomass components to syngas, an important chemical intermediate used to make synthetic natural gas, ammonia, methanol and other chemicals. |
| Sironix Renewables | 2017 February | Various: Paul Dauenhauer, Christoph Krumm, Christine Joseph, Dae Sung Park, Dionisos Vlachos, Raul Lobo, Muara Koehle | Combines plant-based ingredients into functional chemicals that will change the way in which we make laundry detergents, produce safer agricultural pesticides, and even improve how oil spills are cleaned up. |
| Resynergi | 2017 February | Ruan, Roger | Resynergi converts waste plastic to oil using microwave pyrolysis technology. |
| Cleanair-CARE LLP | 2016 September | Various: Charles Lo, David Pui, Tom Kuehn, Sheng-Chieh Che | Renewable, energy efficient method to clean large amounts of outside air specifically targeting urban air in Chinese cities such as Beijing. Uses an adaptive spray array to remove particulate matter from the air. |
| Valerian Materials | 2016 February | Various: Marc Hillmyer, Frank Bates, Kechun Zhang | Monomer and polymer components for high performance, biodegradable plastics from renewable, green feedstocks. |
| ThermChem | 2015 October | Various: Steven Heilmann, Kenneth Valentas | Energy efficient method for reducing wastewater sludge from municipal and agricultural sewage wastes and recovering lipids, phosphorus and nitrogen. |
| Minnepura | 2013 October | Various: Al Aksan, Larry Wackett, Michael Sadowsky | Encapsulation of biomaterial that provides an effective, low cost treatment solution to customers who need to remove hydrocarbons and chemicals from water. |
| NH3 Strategies | 2013 October | Ruan, Roger | Process for producing ammonia fertilizer with water and air that can be implemented close to farmers. |
| Ascenix Biotechnologies | 2013 January | Zhang, Kechun | Process to take sugar-based feedstocks and produce synthetic chemicals for multiple uses including production of high value plastics. |
| Argilex Technologies Corp | 2012 March | Tsapatsis, Michael | Develops a membrane technology for separation processes such as those in the petroleum refining, chemicals, and biofuels industries. |
| TerreCOH (formerly Heat Mining Company) | 2012 March | Saar, Martin | Uses sequestered carbon dioxide to extract geothermal energy from the earth that is used to generate electricity. |
| cycleWood Solutions | 2011 September | Sarkanen, Simo | Creates low-cost biodegradable and compostable bags. |
| Renovo Water (NewWater) | 2010 June | Various: Larry Wackett, Michael Sadowsky | Developing a new type of drinking water filter. |
| BioCee | 2009 May | von Keitz, Marc | Cost-effective and environmentally sound production of clean fuels, chemicals, and water treatment by harnessing the full biocatalytic potential of microorganisms. |
Engineering & Physical Science
Description | |||
|---|---|---|---|
| LEAP Photonics, Inc. | 2025 January | Li, Mo | Advancing cost-effective, high-performance LiDAR solutions for automation and robotics. |
| Uniqomp, LLC | 2024 August | Bazargan, Kia | A field-programmable gate arrays for advanced mathematical functions useful in artificial intelligence, investment and finance, and robotics. |
| PHOS | 2023 August | Elmer-Dixon, Margaret | PHOS is developing a method to measure plastic degradation using a topical chemical combined with AI leveraging standard visual sensors (Phones/Cameras). PHOS tech can inspect plastic coatings in infrastructure or be used in manufacturing spot checks. |
| Particle4X | 2023 April | Hong, Jiarong | Air borne particle analysis tool using a 3D imaging sensor based on digital inline holography (DIH) for measurements of size distribution, shape, concentration and other physical properties. |
| ANAFLASH | 2022 November | Kim, Chris | Developing semiconductor solutions for smart edge IoT devices. |
| Intermix Performance Material | 2021 January | Bates, Frank | Technology that increases the efficiency and cost effectiveness of recycling post-consumer mixed plastic waste by producing a higher quality resultant resins that deliver a superior performance polymer alloys comprised of polypropylene and polyethylene. |
| ZeroTabs | 2020 December | Various: Amrit Supriya, Trung Ha | Ergonomic standing desk. |
| Counterflow Technologies | 2020 January | Various: Alison Hoxie, Paul Strykowski, and Vinod Srinivasan | Spray nozzles for liquids which use less air, pressure and energy to apply a range of low and high viscosity liquids. These nozzles can be retrofitted to most, if not all, existing spray installations. |
| Grip Molecular Technologies | 2019 December | Various: Steve Koester, Sang-Hyun Oh, Mike McAlpine | A graphene-based sensor that enables lower cost, higher performance testing for infectious disease diagnostics. |
| Carpe Diem | 2019 November | Various: Lorraine Francis, Dan Frisbie | Self-aligning roll-to-roll nano imprint lithography and atomic layer deposition systems and technologies used to make flexible hybrid electronics, optics and functional surfaces. |
| MerTron, LLC | 2017 June | Various: Sandra Myers, David Bowles, Jim Marti | A technology that captures mercury when a human body is cremated, thus eliminating any mercury escaping into the atmosphere. |
| Aerem, LLC | 2017 April | Various: David Pui, Qisheng Ou, Qingfeng Cao | Developing an advanced gas particulate filter system for vehicles to address stringent emissions requirements in China. |
| House 3 (Carponentry, LLC) | 2017 April | Donahue, Patrick | Designs, processes and equipment to enable the building of distributive production capacity for a unique residential housing product for the single family detached market. |
| Ensor, Inc. | 2016 July | Kortshagen, Uwe | Battery chemistry and manufacturing process for a silicon dominant based anode that will triple the anode energy density and provide minimal loss in capacity retention. |
| Bolder Flight Systems | 2016 March | Various: Brian Taylor, Chris Regan | Company provides software and hardware for a variety of Drone navigation products and systems. |
| Advanced Road Patch | 2016 March | Zanko, Lawrence | Application of magnetite (taconite) for use in material for road repair. |
| Innotronics | 2015 October | Rajamani, Rajesh | Engineered sensing solutions for non-contacting position measurement. |
| Adama Materials | 2015 January | Various: Chris Macosko, Andreas Stein | Improves the properties of resin and fiber composites, such as epoxy/carbon fiber and polyester/fiberglass, at very low cost. |
| Bennett Autogas Systems | 2014 June | Bennett, David | Fuel tank that is lower cost and has reduced maintenance for liquid petroleum fueled vehicles. |
| Niron Magnetics | 2014 June | Wang, Jian-Ping | New material and process to fabricate permanent magnets, eliminating the need for rare earth elements. |
| SMART Signal Technologies | 2011 October | Liu, Henry | Offers a hardware and software solution that can be used to reduce traffic congestion on major signalized arterial highways. |
| Upstream Technologies | 2011 February | Gulliver, John | Sediment control in stormwater systems. |
| United Science | 2010 November | Buhlmann, Phil | Reducing pollution through high accuracy measurement for chemical ions. |
| Ascir | 2009 February | Talghader, Joey | Revolutionary solid state semiconductor-based gas detector capable of monitoring the presence of hazardous gases at a safe distance. |
| Rushford Hypersonic | 2008 March | Girshick, Steve | Coating technologies which are harder, denser and more fracture resistant than standard carbide coatings, used in the industrial tooling industry. |
| Recon Robotics | 2006 November | Papanikolopoulos, Nikolaos | Creates devices used by the US military, federal, state and local law enforcement agencies to protect their personnel, minimize collateral damage and gain immediate reconnaissance within dangerous and hostile environments. |
Food & Agriculture
Description | |||
|---|---|---|---|
| ZaNe Genetics | 2024 October | Smanski, Michael | Use of large black soldier fly larva to produce omega-3 oils for use in dietary supplements. |
| Convergent Bioscience | 2024 February | Haynes, Christie | Silica Nanoparticles (SNPs) derivatives that can improve plant health and vigor by creating a platform technology that can interact with other compounds to impact plant health. |
| Verilytix | 2022 June | Krueger, Quinton | AI solutions for Cannabis growers. Increases yield, reduces production costs. |
| NovelSoy | 2021 December | Lorenz, Aaron | Commercialization of high-oleic soybeans. |
| Understanding Dairy Markets | 2021 June | Bozic, Marin | Service business to subscribers that monitors and publishes information related to the dairy industry. |
| Nutricepts LLC | 2020 January | Various: Lloyd Metzger, Donald A. Grindstaff | Provides unique, value-added food ingredients such as an additive to improve cheese taste, quality and consistency. |
| Insight Sensing | 2019 July | Various: Carl Rosen, Tyler Nigon | Precision agriculture software for nutrient management enabling remote sensing to predict crop nitrogen status. Insight Sensing was acquired by Sentera in 2021. |
| Jord BioScience | 2019 April | Kinkel, Linda | Biological plant control mechanism that promotes increase crop yields with a mixture of bacteria that can be optimized for a specific crop and for a specific set of physical and environmental conditions. |
| Planetarians | 2017 December | CFANS Food Science and Nutrition | Planetarians makes plant-based chips from up-cycled sunflower oilcake meal. Planetarians shows that repurposing oilcakes from an animal into the human food can feed up to 1.5B extra people without growing extra crops. |
| Good Libations | 2016 May | Peterson, Devin | Food additive that addresses problems with harsh taste for various consumable liquids. Initial focus on dark alcohols. |
| Carp Solutions | 2015 February | Bajer, Pzemyslaw | Field sampling with analytics to develop sustainable management strategies for invasive fish such as carp. |
| Veterinary Diagnostics and Therapeutics | 2013 May | Conzemius, Michael | Genetic test that assesses risk for rupture of the cranial cruciate ligament in dogs. |
| NovaMela | 2013 April | Various: James Luby, David Bedford | Umbrella entity for leading apple companies in Italy that cultivate and sell promising new apple varieties including SweeTango. |
| The Actives Factory | 2012 October | Krasutsky, Pavel | Natural anti-inflammatory compound for the cosmetics, dietary supplements and pharmaceuticals industries. |
Medical Devices
Description | |||
|---|---|---|---|
| GlioStim Medical Systems | 2024 September | Chen, Clark | Technology for treating solid tumors (founded by Joe Hofmeister) |
| OralMR LLC | 2024 October | Nixdorf, Donald | Small, low cost, minimal viable dedicated dental MRI for imaging inflation and soft tissues. Company co-founders are Don Nixdorf and Beth Gronke |
| MotionMedix LLC | 2024 September | Various: Ebbini,Emad; Aldiabat, Hasan; Casper, Andrew; Liu, Dalong; O'Brien, Parker | MotionMedix is using ultrasound imaging to measure hydration and biomarkers for the ICU and Sports Medicine |
| NeoAcoustic Inc | 2024 May | Lim, Hubert | Ultrasound hearing aid delivers ultrasound stimulation to present waves and vibrations in the brain fluids, which in turn vibrate cochlear fluids through the inner ear canal/aqueduct, thus activating the auditory brain and inducing hearing in the brain. |
| Optimal Mobility LLC | 2024 March | McCracken, Patricia | Pediatric standup wheelchair. |
| HiFi Imaging LLC | 2024 March | Akcakaya, Mehmet | MRI software and pulse sequences that leverage AI-based approaches to improve scan time, image quality, and acoustic noise on standard MRI scanners. |
| Glome Health | 2024 February | Yekinni, Ibrahim | Prevents patients from developing infections from the connecting/disconnecting process during a peritoneal dialysis session. |
| NuSonex | 2023 December | Ebbini, Emad | Dual Mode Ultrasound Array (DMUA) ultrasound to diagnose and treat myofascial pain. First indication is lower back pain with a desktop clinic system. Second indication is neck pain. |
| Magtection | 2023 December | Wang, Jianping | A novel magnetic particle spectroscopy (MPS) diagnostic device that provides an inexpensive, portable, quantitative and rapid turnaround time to address present diagnostic challenges in human, animal health and community or herd diagnostic sampling. |
| BrainSpec | 2023 November | Oz, Gulin | MRI spectroscopy software solution compatible with the major MRI scanners to perform a virtual biopsy on a wide range of neurological disorders and traumatic brain injuries. |
| PhysiAroma | 2023 October | Groenke, Beth | Advancing a medical device to help millions suffering with chronic pain. The integration of pain management techniques, novel scent delivery and AI creates a scalable solution expanding individual's ability to control their pain. |
| Safeguard Medical | 2023 August | Seppelt, Andi | Safeguard Medical is working to improve safety of nurses, police officers and teachers with a device that is easily deployed to subdue violent patients and/or individuals without restricting that individual's breathing or causing additional injuries. |
| Vista Biomedical | 2023 July | Various: Joe Weber, Sandy Liu, Beth Groenke | Developing a urinary diagnostic/screen that uses your cell phone camera to interpret the test results for at home testing and screening of common conditions. |
| Faberge Fertility | 2023 June | Broberg, Dan | An In-Vitro Fertilization (IVF) Embryo Transfer Catheter that uses the embryo culture media rather than air. |
| OmniKog | 2023 April | Lim, Kelvin | Cognitive neuromodulation system used to treat patients with mental health disorders. The first targeted mental health disorder indication will be treating substance abuse addiction. |
| Objective Biotechnology | 2023 March | Bangalore Kodandaramaiah, Suhasa | Robotic platform for high throughput single cell gene manipulation in intact tissue that is faster and yields better results than current practices. |
| Kantika | 2023 February | Various: Gianluigi Veglia, Manu Veliparambil Subrahmanian | AI technology that optimizes MRI RF pulses by applying novel RF pulses to significantly reduces MRI scan time and improves image quality. |
| MR Access | 2023 February | Vaughan, Tommy | Low cost, full body MRI that is the size of and portability of a half shipping container. It uses the cloud and remote radiologists to provide MRI services in clinics and healthcare provider locations where MRI has never been possible. |
| Granite Mountain Medical | 2023 February | Medical Device Center Fellows | A urinary catheter stabilizer that addresses severe urethra erosion due to long term catheterization. |
| Adialante | 2023 January | Garwood, Mike | MRI technology that significantly reduces hardware cost and size by eliminating the need for gradient coils, one of three basic components in MRI scanners. |
| VOCxi Health | 2022 November | Medical Devices Center | Breath diagnostic system with first indication for early detection of lung cancer. |
| Alexandria BioTech | 2022 October | Selim, Ahmed | Cardiopulmonary resuscitation catheter device for interim cardiac arrest treatment between manual chest compressions and full ECMO. |
| MAP/PATH | 2022 August | Sreevatsan, Srinand | Provides accessible, over the counter diagnostics for mycobacterium infections, including tuberculosis(TB). |
| UltraHearing Technologies | 2022 July | Lim, Hubert | Hearing improvement platform with applications to treat tinnitus, hearing loss, and replace hearing aids. |
| Rehabnetics Medical | 2022 May | Konczak, Juergen | Rehabilitation device that uses gamification and wrist motion to accelerate and improve recovery from strokes. |
| Adapt Design Works | 2022 March | Various: Timothy Truty, Gary Goldish, Christine Olney, Alexandra Bornstein, Andrew Hansen | Pressure mapping technology for wheelchairs helping patients reduce pressure points that can lead to reduced pressure sores. |
| Champaign Imaging | 2022 March | Garwood, Mike | Improvements to MRI systems that reduces impact of patient movement targeted as pediatric patients thus reducing need for repeated scans. |
| AxionBio | 2021 November | Ebbini, Emad | Magnetic stimulation device for non-invasive stimulation of the phrenic nerve to exercise the diaphragm thus weaning a patient off a ventilator faster. |
| Fasikl | 2021 July | Yang, Zhi | A peripheral neural interface Computer-On-a-Chip that, when paired with a neural cuff, enables new levels of neural communication both into and out of the human body potentially enabling prosthetic limbs to have human like functionality. |
| VitriStor | 2021 June | Bischof, John | Proprietary approach to significantly increasing the viability of cells in the Freezing and thawing process for liver cells. |
| Habit Camera | 2021 February | Various: Andrew Hansen, Gary Goldish (VA/UMN) | Low-cost, wireless camera that is optimized for skin inspection and telehealth patient care. |
| Aspire Air | 2021 February | Hogan, Christopher | Portable hood that covers a patient’s head while in a hospital bed reducing the spread of infectious disease. Vents to an external filter, allows caregivers access to the patient. |
| Owl Navigation | 2020 July | Various: Noam Harel, Guillermo Sapiro | Brain maps for accurate location and targeting for deep brain stimulation used with patients for non-Parkinson’s indications. |
| 2nd Wave | 2020 February | Lim, Hubert | Coordinated ultrasound and electrical stimulation of spleen to reduce inflammation and treat autoimmune disorders. |
| Stim Sherpa | 2019 December | Various: David Darrow, Logan Grado, Andrew Lamperski, Tay Netoff, Bryan Moore | Software that provides individualized, optimum device performance using a Bayesian optimization algorithm that learns patient preference for spinal cord stimulators in paraplegics and for deep brain stimulators (DBS) for epileptic patients. |
| Aperios Technologies | 2019 October | Yang, Zhi | Digital-to-Analog solution enabling a neuromodulation therapy to control pain. |
| Reprise Biomedical | 2019 July | Various: Doris A Taylor, Harold Ott | Develops, manufactures and sells medical devices based on perfusion decellularization technology that supports cellular integration with initial focus on soft tissue repair for reinforcement in plastic and reconstructive surgery and wound care. |
| Hybridge Medical | 2019 June | 2018 Medical Device Center Fellows | Tool for taking biopsy samples from the lung. |
| Invisian | 2019 February | Various: Laura-Lee Brown, Alan Johnson, Samuel Levine, Christopher Roffas | An orthodontic device system for simplified jaw fixation. |
| Interventional Pulmonary Solutions | 2019 February | Various: Felix Landaeta, Roy Cho, Doug Devens | Medical device for placement, repositioning or removal of central airway stent. |
| BGK, LLC | 2019 January | Various: Matt Kudek, MD 2018 Medical Device Center Fellow | lntraoral device offers targeted drug delivery when placed in the mouth between the upper and lower teeth. |
| Aurora Concussion Therapy Systems | 2018 December | Various: Shannon Smith, Kevin Goodwin, Medical Device Center Fellows | Technology to speed concussion recovery using infrared light therapy. |
| Sollievo Pharmaceuticals | 2018 December | Various: Ronald Siegel, James Cloyd | Novel compound and proprietary intranasal drug delivery device for treating epilepsy and other indications. |
| RetiSpec Inc | 2018 September | Vince, Robert | Alzheimer Diagnostic that uses images of the eye and software to analyze the image to provide a very early detection of the onset of Alzheimer's at a stage where intervention may reduce progression. |
| Cerovations | 2018 August | 2017 Medical Device Center Fellows | Implanted, redundant drain line from the brain to the abdomen to improve the drainage of fluid off the brain after trauma. |
| Simagine Medical | 2018 June | Various: Robert Sweet, Troy Reihsen | Tools and systems for simulating healthcare procedures and treatments that improves the delivery of procedure reducing errors and improve efficiency. |
| Prescix Medical | 2018 May | Devens, Doug (MDC Fellow) | New process/technique that cleans and sterilizes flexible ureteroscopes reducing healthcare risk associated with contamination including debris, residue, and bacteria. |
| Yonder | 2017 December | 2017 Medical Device Center Fellows | An application that runs on a tablet device for children to use before they visit the dentist with the objective of reducing the anxiety brought on by the pending visit. |
| Vascudyne, Inc | 2017 July | Various: Bob Tranquillo, Zeeshan Syedain, Lee Meier | Surgically implantable heart valves and arteries made from decellularized tissue tubes. These assimilate to the cardiovascular structure and grow with the patient - ideal for children needing heart repairs that can grow with them. |
| Cell Therapy Solutions | 2017 January | Hubel, Allison | Device that reduces cell loss, processing time, and labor costs for multiple types of cryopreserved cells (e.g., stem cells and blood cells). |
| Soundly | 2016 December | Various: Brian Krohn, Adam Black, Medical Devices Center fellows | Soundly is a simple, non-invasive way to reduce snoring using an app on your smartphone. Backed by evidence-based sleep medicine research, the app engages the user in fun snore-reducing exercises. |
| Digital Design Studios | 2016 April | Lutfy, Patricia | Orthotic targeted at people who suffer from bunions, aiding in comfort and facilitating an active lifestyle. |
| EmboMedics Gel Therapies | 2015 December | Golzarian, Jafar | Natural resorbable gel product that is used to deliver therapeutic drugs into the body for various treatments, including pain. EmboMedics was acquired by QX Medical in May 2019. |
| Stimdia (Andarta) Medical | 2015 April | Various: James Krocak, Jesus Cabrera, John Ballard | Non-invasive lung pacing device that reduces the time a patient uses a ventilator and saves significant costs. |
| Blossom Medical | 2014 July | Medical Device Fellows 2012 | Neonatal medical device that cradles and supports infants during early stage of life. |
| Minnscan | 2014 May | Various: Michael Garwood, Donald Nixdorf | Advanced imaging system for using MRI in dental applications. |
| MesoFlow | 2014 May | Hubel, Allison | Device that reduces cell loss, processing time and labor costs for multiple types of cryopreserved cells (e.g., stem cells and blood cells). |
| Vigilant Diagnostics | 2014 April | Bischof, John | Lateral flow assay system (diagnostic) that improves sensitivity of standard lateral flow assays by 10 to 100 times. |
| Zepto Life Technology | 2014 March | Wang, Jian-Ping | Animal and human diagnostic solution that is accurate and highly sensitive for central lab, clinic, and point-of-care applications. |
| ReMinD Technologies | 2013 June | 2012 Medical Device Fellows | Developing, manufacturing and marketing consumer technologies to help patients and caregivers ensure medication adherence. |
| EmboMedics ResoSpheres | 2013 April | Golzarian, Jafar | Natural, resorbable polymer bead used to cut off blood supply to tumor/cancer cells in the body. EmboMedics was acquired by QX Medical in May 2019. |
| Universal Magnetic Systems | 2013 March | Wang, Jian-Ping | Superior, high moment magnetic nanoparticles for disease detection and diagnostic target separation. |
| FocusStart | 2013 February | Rajamani, Rajesh | Handheld probe that measures tension in soft tissues, such as tendons and ligaments, during invasive orthopedic surgery. |
| Andas | 2012 December | Koester, Steven | Technology that conveniently communicates accurate level of intoxication via breath analysis through smart phones. |
| Aria CV | 2011 May | Second-year Medical Device Fellows | Medical device to treat pulmonary hypertension. |
| International Cardio Corp | 2010 December | Ebbini, Emad | Ablating vascular plaque utilizing high intensity focused ultrasound. |
| XO-Thermix Medical | 2010 June | Cressman, Erik | Developing a unique airway thermoplasty device intended to become the standard of care in improving airway function for millions of patients with severe, persistent asthma. |
| Miromatrix Medical | 2010 February | Taylor, Doris | Human organs for transplantation, manufactured using decellularization/recellularization technology. Miromatrix went public with an IPO in June 2021 under the symbol MIRO. |
| R8Scan | 2009 August | Srienc, Fredrich | Cytometry instruments that track and measure individual cells, providing detail into the dynamics of cellular growth. |
| Orasi Medical | 2007 September | Georgopoulos, Apostolos | Diagnostic tests that detect the unique disruptions in the electrical activity of the brain caused by Alzheimer’s disease to aid a physician in the early diagnosis and initiation of treatment of patients. |
| Steady State Imaging | 2006 December | Garwood, Michael | Novel magnetic resonance imaging (MRI) technology. Steady State Imaging’s assets were acquired by GE Healthcare in April 2011. |
Software & IT
Description | |||
|---|---|---|---|
| SmartPal | 2025 February | Liu, De | AI student support plugin for Canvas and other learning management systems. |
| Emet Surgical, Inc. | 2024 October | Papanikolopoulos, Nikolaos | AI driven navigation system for tumor removal and tumor identification during minimally invasive surgery. |
| Social Value, Inc. | 2024 August | Srivastava, Jaideep & Khan, Euna | Leverages proprietary algorithm to develop software that augments marketing and social analytics for enhanced operations. |
| Flyover Country, LLC | 2024 January | Various: Amy Myrbo, Shane Loeffler | Software development company supporting requests for data and updates to UMN's NSF funded popular Flyover Country App. |
| DecoGenomics | 2023 December | Faulk, Chris | DecoGenomics is a small business created by the researcher to respond to non-research requests to his lab related to DNA sequencing. |
| Nu Compaction | 2023 December | Sun, Calvin | Nu Compaction is a software company focused on simulating the longevity of powder compaction. Numerous applications including soaps, explosives & pharmaceuticals. |
| Xanthos Health | 2022 January | Various: David Haynes, Pinar Karaca Mandic | The platform supports information sharing between mobile apps, EHR apps and organization apps with enhanced features like filtering, push notifications, and alerts that notify organizations and providers of patient needs. |
| Reflective Performance | 2021 September | Various: Stephanie Carlson, Phil Zelazo | Productivity tools to improve workforce management (recruitment, retention, development, performance) that measures and improves Executive Function (EF) — the attention-regulation skills used in goal-directed problem-solving and emotional control. |
| TerraCover | 2021 September | Various: Ankush Khandelwal, Vipin Kumar | Physics guided machine learning for satellite imagery analysis at global scale, built on decades of University research on land cover change detection. |
| Savvy Systems | 2021 June | Hepburn, Ken | Culturally-adapted, multi-translated, and nationally adopted education solutions for family caregivers of Alzheimer’s and dementia patients. |
| Q-Rounds | 2021 May | Various: Michael Pitt, John Sartori | Web-based inpatient virtual queue and communications platform that decreases costs and medical errors by increasing efficiency and satisfaction of the inpatient hospital rounds experience. |
| Exergi Predictive | 2020 September | Northrup, Will | Data analytics system to Improve vehicle fuel and/or electric efficiency of hybrid electric trucks used in commercial applications such as last-mile delivery and fleet services. |
| Speech & Language Collaborative | 2020 June | Clinical and Translational Science Institute | Unique, child-friendly, software tools that are used with autistic children to help them adapt to changing activities and environment. |
| Track AI | 2020 May | Unver, Baris | Leverages artificial intelligence to enhance public safety by transforming surveillance into actionable insights. Focused on crime prevention and detection, it empowers law enforcement to analyze video and data efficiently, increase accuracy, and reduce human error and reliance for faster, data-driven decisions. |
| Training+U | 2020 February | Cline, Heather | Training tools for parent involvement in family training for self-reflection and dialog. |
| Nfluence Analytics | 2019 November | Srivastava, Jaideep | AI software algorithms that aid digital marketing firms in targeting high value customers. |
| Belalcazar Consulting | 2019 April | Various: Robert Patterson, Li Wang, Andres Belalcazar, Fei Yang | Software measuring thoracic impedance that provides information on fluid load in patients with heart failure. |
| Sciamble, Inc | 2019 January | Various: Ned Mohan, Siddharth Raju | Simulation software with hardware integration for real-time controllers. To be used in high school and undergraduate programs. |
| eaterpad | 2018 September | Nutrition Coordination Center | eaterpad is an app that will help you better understand your eating habits by using nutritional data from the UMN Nutrition Coordination Center. |
| Flyover Country, Inc. | 2018 June | Various: Amy Myrbo, Shane Loeffler | Software application for consumers who fly that gives them interesting information on geographic points of interest as they fly over the location. |
| Dridam | 2018 April | Candler, Graham | Enhancement to US3D software models enabling scalable and more flexible identification of high-speed aerodynamics and aerodynamic heating problems faster and more accurate. |
| PeopleStat | 2018 March | Siegel, Ron | Collects and analyzes anonymized data streams and couples with machine learning to provide feedback to people who are either pre-diabetic or actively diabetic so that they can make appropriate lifestyle changes. |
| Daynamica | 2018 March | Fan, Yingling | Smartphone application for capturing travel data and user experience for data gathering and research applications in transportation and logistics. |
| Farm Vision Tech, Inc | 2017 June | Various: Volkan Isler, Patrick Plonski | Imaging software that works with existing drones and their imaging technology to provide farmers a view on crops. Aids on prep and plans for harvesting. |
| Turing Tumble, LLC | 2017 May | Various: Paul Boswell, Jiaoyang Li | An interactive , educational board game that when complete, simulates the way computers work. |
| VirtusAero, LLC | 2017 April | Various: Graham Candler, Heath Johnson, Pramod Subbareddy, Loannis Nompelis, Travis Drayna | Provides support for corporate, government, and academic users of US3D. The US3D software models heat flows at supersonic flight speeds for research, military, and commercial applications. |
| R5VR | 2016 December | Anderson, Lee | Software interfaces and service that take architectural drawings and create a VR experience so clients can VR the space they are going to build. |
| LEIF (Sustainalytics) | 2016 November | Various: Rylie Pelton, Andrew Fang, Mark Reiner | Assists cities and communities in the assessment of environmental and social impact of infrastructure projects. Services include: environmental footprinting, sustainability action analysis and data trend visualizations. |
| Modus (BSTM) | 2016 June | Carlson, Lockwood | Delivers "Technology Foresight" — a product for enterprise companies that enables forecasting, strategic planning, R&D strategy, and decision-making of their technology roadmaps. |
| ProValens | 2016 January | Gaugler, Joe | Provides a shared database of resources to caregivers to share with patients that provides relevant information curated by the caregiver. |
| UpTern | 2015 August | Taylor, Brian | B2B aerial inspections and data analytics of large infrastructure (pipelines, transmission lines, rivers, roads, and railways. |
| Andamio Games | 2015 June | Dubinsky, Janet | Interactive game-like approach to teaching neuroscience and mental health concepts. |
| Target Genomics | 2015 April | Van Ness, Brian | Resource database, a decision support system and services for healthcare providers and patients on use of genomics. |
| FastBridge Learning | 2015 March | Christ, Ted | Automated K-12 assessment tools for student screening, progress monitoring, and program evaluation. Fastbridge was acquired by Illuminate Education, a leading provider of education technology for grades K–12, in June 2019. |
| Flipgrid (formerly Vidku) | 2015 February | Miller, Charlie | Platform allowing individuals to engage in rich, video-based dialogues with others organized around topics and questions. Flipgrid was acquired by Microsoft In June 2018. |
| Early Movement Monitoring Assessment (EMMA) | 2014 September | Leitschuh, Carol | Individual Growth Development Indicators (IGDIs) for infants monitoring early movement. |
| PSI (STA) | 2014 August | Various: Shyam Boriah, Vipin Kumar, Karsten Steinhaeuser | Satellite image analysis algorithm to detect changes in resources (forest, crops, water, urbanization). |
| Reflection Sciences | 2014 August | Various: Stephanie Carlson, Phil Zelazo | A method to test a child's ability to concentrate on a task. |
| Efficient Windows Collaborative | 2014 May | Various: Kerry Haglund, John Carmody | Website providing unbiased information on the benefits of energy-efficient windows, descriptions of how they work, and recommendations for their selection and use. Efficient Windows Collaborative was acquired by NFRC. |
| Treatment Global | 2014 May | Peterson, Kevin | Multi-disciplinary telehealth approach that provides chronic disease and health and wellness management without the need for a clinic visit. |
| InformeDesign | 2013 October | Various: Caren Martin, Denise Guerin | Searchable database that facilitates designers’ use of current, research-based information as a decision-making tool. |
| Surgical Information Sciences | 2013 October | Various: Noam Harel, Guillermo Sapiro | Brain maps for accurate location and targeting for deep brain stimulation used with patients who have Parkinson’s disease. |
| CVC Heartsavers | 2013 October | Cohn, Jay | Diagnostic that provides earlier intervention and treatment for cardiovascular disease. |
| Applied Informatic Solutions | 2013 June | Various: Jason Nikas, Walter Low | Informatics tools to assist with the identification of high-value biomarkers. |
| Medjules (Synaptic Design) | 2013 June | 2013 Mechanical Design Class | Surgical training platforms that provide quantifiable feedback for medical students and practicing physicians. |
| Evidentia Health | 2013 April | Steinberger, Dan | Evidence-based clinical decision support tools for radiologists at the point of care. |
| Omicron Health Systems | 2012 June | Peterson, Kevin | Technology that helps clinicians facilitate randomized controlled trials and translates research into clinical practice. |
| Early Learning Labs | 2012 March | Various: Scott McConnell, Alisha Wackerle-Holman | Assessments and services to help parents and early child-care providers develop “kindergarten-ready” children. myIGDIs was acquired by Renaissance in April 2019. |
| Drive Power | 2011 December | Various: Max Donath, Craig Shankwitz, Alec Gorjestani | Develops unique products that leverage emerging measurement technologies and predictive analytics to enable people to make more informed driving decisions. |
| VitalSims | 2011 December | Various: Paul Johnson, George Biltz | Enables the observation, analysis, and improvement of physician decision making in a simulated practice setting. |
| Ninja Metrics | 2011 June | Srivastava, Jaideep | Online social networking and gaming analytics, predicting user behavior. |
| Clinical Innovation Labs (IBU) | 2010 September | Peterson, Kevin | Healthcare IT solution for clinical trial recruitment and physician quality reporting. |
| Early Learning Labs (IBU) | 2010 May | Various: Scott McConnell, Alisha Wackerle-Holman | Assessments and services to help parents and early child-care providers develop “kindergarten-ready” children. Early Learning Labs (IBU) was acquired by myIGDIs and operated under a new license from March 2012 through April 2019 when myIGDIs was acquired by Renaissance Learning, Inc. |
| Nouvant (CaSTT IBU) | 2010 February | Huebsch, Rick | Web-hosted, subscription-based, search engine optimization tool for intellectual property marketing, licensing and tech transfer. |
| Medication Management | 2006 April | Cipolle, Bob | Comprehensive, patient-centered medication therapy management services that identify and resolve drug therapy problems. Medication Management was acquired by Genoa Healthcare in July 2017. |
Questions?
Contact [email protected] to schedule an appointment and learn more.