Congratulations to these UMN researchers who were awarded patents for their discoveries! In 2025, UMN researchers were issued 105 US patents (foreign patents not included).
Jump to patents in:
- Engineering, Physical Sciences, or IT
- Food, Ag-Tech, and Natural Resources
- Human or Animal Health Sciences
Receiving a patent is an intellectual achievement for any researcher and a key commercialization milestone. A patent allows a discovery to be shared with the rest of the world and advances innovation in and across important fields and industries, including health care, the environment, education, and food production.
US patent listings are publicly available through the USPTO Patent Public Search. See these Resources for Inventors to learn more about the UMN technology commercialization and patent process.
Engineering, Physical Sciences, or IT
Chitosan-Coated Silica Nanoparticles for Enhanced Crop Application
Issued: 1/7/2025
Inventors: Christy Haynes; Chuanxin Ma; Jason White; Joseph Buchman; Wade Elmer
Patent number: 12187658
Active Knit Compression Stockings
Issued: 1/28/2025
Inventors: Brad Holschuh; Julianna Abel; Kevin Eschen; Rachael Granberry
Patent number: 12209336
Estimation of In-Cylinder Pressure and Combustion Variables from Non-Intrusive External Sensors in a Diesel Engine
Issued: 2/4/2025
Inventors: Rajesh Rajamani; Woongsun Jeon
Patent number: 12215642
Tuning Medical Device Parameters with Bayesian Optimization
Issued: 2/4/2025
Inventors: Andrew Lamperski; Bryan Moore; Logan Grado; Tay Netoff
Patent number: 12214201
Highly Stable Protein-containing Bioactive Coatings and Materials
Issued: 2/11/2025
Inventors: Andreas Buthe; Hongfei Jia; Masahiko Ishii; Minjuan Zhang; Ping Wang; Songtao Wu
Patent number: 12221593
Efficient Valve Seat Design for Small Displacement Actuators
Issued: 2/18/2025
Inventors: Matthew Gallagher; Nathan Paul Hagstrom; Thomas Chase
Patent number: 12228222
One-Step Route to High Modulus and Highly Conductive Polymer Electrolyte Membranes
Issued: 3/11/2025
Inventors: Lucas McIntosh; Marc Hillmyer; Morgan Schulze; Tim Lodge
Patent number: 12249688
Polyethylene and Polypropylene Block Copolymers
Issued: 3/11/2025
Inventors: Anne LaPointe; Frank Bates; Geoffrey Coates; James Eagen
Patent number: 12247092
A Distribution-Invariant Data Protection Mechanism
Issued: 3/11/2025
Inventors: Xiaotong Shen; Xuan Bi
Patent number: 12248613
Snowplow Driver Assist System (DAS)
Issued: 3/11/2025
Inventors: Brian Davis; Chen-Fu Liao; Katelyn Schwieters; Max Donath; Nichole Morris
Patent number: 12246597
Low-loss Nanowire Coplanar Waveguide Interconnects for Sub-Terahertz Applications
Issued: 3/18/2025
Inventors: Aditya Dave; Allison Harpel; Bethanie Stadler; Nikita Mahjabeen; Rashaunda Henderson; Rhonda Franklin; Yali Zhang
Patent number: 12255108
Strategic Optimization of Wind Farm Energy Production
Issued: 3/18/2025
Inventors: Jiarong Hong; Linyue Gao
Patent number: 12253063
A Delay Based Coupling Weight Circuit for Coupled Ring Oscillator Based Ising Machines for Quantum-inspired Computing
Issued: 3/25/2025
Inventors: Chris H. Kim; William Moy
Patent number: 12261598
Algal Strains that Produce Simple Sugars at Physiological pH
Issued: 4/8/2025
Inventors: Brett Barney; Evelyn Vogel; Natalia Mancipe
Patent number: 12270063
Methods of Making Porous Nanocomposites Sorbents for Multipollutant Capture
Issued: 4/15/2025
Inventors: Abdennour ABBAS; Fatemeh Heidari; John Brockgreitens; Snober Ahmed
Patent number: 12274995
Multiblock Copolymers as Adhesion Promotors and Compatibilizers for Recycled Multicomponent Polymer Products
Issued: 4/22/2025
Inventors: Christopher Ellison; Kevin Miller
Patent number: 12281204
Pulse-Based Convolution for Near-Sensor Processing in Unary Computing
Issued: 5/13/2025
Inventors: David Lilja; Kia Bazargan; Mohammadhassan Najafi; Sayed Abdolrasoul Faraji
Patent number: 12299556
Nanobreadboards with Nanomagnets for Localized Heating
Issued: 5/13/2025
Inventors: Bethanie Stadler; Rhonda Franklin
Patent number: 12300591
Multifunctional (Composite) SMA Yarns
Issued: 5/13/2025
Inventors: Brad Holschuh; Charles Weinberg; Julianna Abel; Justin Barry; Rachael Granberry; Santo Padula II
Patent number: 12297593
Method of Improving the Efficiency of Axial-Piston Hydraulic Motors
Issued: 6/3/2025
Inventors: Evan Sand; Perry Li
Patent number: 12320412
Graphene-Based Dielectrophoresis Sensor
Issued: 6/10/2025
Inventors: Sang-Hyun Oh; Steven Koester
Patent number: 12325031
Methods for Reprocessing Cross-Linked Polyurethane Foam into Film Morphology
Issued: 6/10/2025
Inventors: Christopher Ellison; David Fortman; Daylan Sheppard; Kailong Jin; William Dichtel
Patent number: 12325778
Data-Informed Energy Management Strategy for Charge Prediction in Battery Electric Vehicles
Issued: 6/10/2025
Inventors: Andrew Kotz; Pengyue Wang; William Northrop
Patent number: 12325322
Polyesters and Polyketoesters from Carbonylative Terpolymerization of Enols
Issued: 6/17/2025
Inventors: Alex Carpenter; Ian Tonks
Patent number: 12331159
High Field Synthesis and Processing of Fe-N Magnets for Improved Properties
Issued: 6/24/2025
Inventors: Craig Bridges; Edgar Lara-Curzio; Gerry Ludtka; Jianping Wang; Lawrence Allard; Michael Brady; Orlando Rios; Xiaowei Zhang; Yanfeng Jiang
Patent number: 12338536
Chemical Sensor based on Aldehyde Receptor Modification of Graphene
Issued: 7/29/2025
Inventors: Blair Troudt; Phil Buhlmann; Steven Koester; Xue Zhen
Patent number: 12369815
Topographically Conforming Garments
Issued: 8/19/2025
Inventors: Brad Holschuh; Julianna Abel; Kevin Eschen; Rachael Granberry
Patent number: 12392063
Fabrication of Anisotropic FeN Permanent Magnet
Issued: 9/9/2025
Inventors: Jianping Wang; Shihai He; Yanfeng Jiang
Patent number: 12412686
Low Temperature Nitriding of Fe-N bulk Permanent Magnetcs
Issued: 9/23/2025
Inventors: Bin Ma; Fan Zhang; Guannan Guo; Jianping Wang; Jinming Liu; Xiaowei Zhang; Yiming Wu
Patent number: 12424358
Non-Pneumatic Lattice Tire with Extreme Asperity Accommodation Capabilities and Resistance to Performance Deterioration from Wear
Issued: 9/30/2025
Inventors: Stefano Gonella; William Zunker
Patent number: 12427809
A Vision-aided Inertial Navigation System for Ground Vehicle Localization
Issued: 10/14/2025
Inventors: Chao Guo; Kejian Wu; Stergios Roumeliotis
Patent number: 12442638
High Efficiency Pump and Motor Utilizing Partial Stroke Piston Pressurization
Issued: 10/28/2025
Inventors: Michael Rannow; Perry Li; Thomas Chase
Patent number: 12454945
Graphene Acoustic Plasmon Resonator for Ultrasensitive Infrared Spectroscopy
Issued: 11/11/2025
Inventors: In-Ho Lee; Sang-Hyun Oh; Tony Low
Patent number: 12468075
Graphene Varactor Gas Sensors Utilizing Hystersis as Mechanism of Detection
Issued: 11/25/2025
Inventors: Greg Sherwood; Justin Nelson; Phil Buhlmann; Qun Su; Steven Koester; Xue Zhen
Patent number: 12480907
Convection-Enhanced Evaporation (CEE) Device
Issued: 12/2/2025
Inventors: Mustafa Kaddoura; Natasha Wright; Prakash Bhalekar
Patent number: 12485362
Stochastic Computing in Computational Random-Access Memory (CRAM)
Issued: 12/9/2025
Inventors: Brandon Zink; Jianping Wang; Yang Lv
Patent number: 12494238
Self-Fitting, Variable-Stiffness Textiles
Issued: 12/9/2025
Inventors: Brad Holschuh; J. Walter Lee; Julianna Abel; Kevin Eschen; Lucy Dunne; Mary Ellen Berglund; Nicholas Schleif; Nicole Ciavarella; Rachael Granberry; Robert Pettys Baker; Sophia Vandycke
Patent number: 12490780
Cyanuric Acid Hydrolase from Bradyrhizobium Japonicum USDA110
Issued: 12/16/2025
Inventors: Feng Guo; Gregory Whited; Jacob Latone; Katherine Hoffmann; Kelly Aukema; Lawrence Wackett; Meng Heng; Rajdeep Dhaliwal
Patent number: 12497315
A Hybrid Reconfigurable Switching Capacitor Structure for Wide Input/Output Voltage Power Converter
Issued: 12/23/2025
Inventors: Peng Fang
Patent number: 12506406
Core-shell FeN Nanoparticles for Permanent Magnets
Issued: 12/30/2025
Inventors: Bin Ma; Jianping Wang; Jinming Liu; Yanfeng Jiang; Yiming Wu
Patent number: 12512238
Food, Ag-Tech, and Natural Resources
Reducing Polyunsaturation and Increasing Oleic Acid Content in Pennycress Oil
Issued: 2/11/2025
Inventors: David Marks; Nicole Folstad; Ratan Chopra; Donald Wyse; John Sedbrook
Patent number: 12221612
MN 1980 Apple Selection ""Triumph""
Issued: 7/15/2025
Inventors: David Bedford; James Luby; Matthew Clark
Patent number: 7868064
MN 1369 Grapevine Selection (green, 'Lumiglo'))
Issued: 7/29/2025
Inventors: Matthew Clark; Jennifer Thull; John Thull;
Patent number: PP36,863
MN 1325 Grapevine Selection (black, 'Shadowglo'))
Issued: 8/19/2025
Inventors: James Luby; Matthew Clark; Peter Hemstad
Patent number: PP36893
Cas-like RNA-directed C2c2-based Gene Modulation in Plants
Issued: 9/2/2025
Inventors: Colby Starker; Daniel Voytas; Feng Zhang; Jonathan Gootenburg; Joseph Belanto; Omar Abudayyeh
Patent number: 12404514
Identification of Reduced Seed Glucosinolate Lines in Pennycress that can Improve Seed Meal Value
Issued: 12/2/2025
Inventors: David Marks; Ratan Chopra; Tim Ulmasov; John Sedbrook;
Patent number: 12484502
MN13142 Potato Variety (Elk River Russet)
Issued: 11/14/2025
Inventors: Carl Rosen; Christian Thill; Laura Shannon; Sanjay Gupta; Scott Garvin
Patent number: PVP No. 202400148
Domesticating Pennycress - Reduced Seedpod Shatter
Issued: 12/30/2025
Inventors: David Marks; Maliheh Esfahanian; Ratan Chopra; John Sedbrook;
Patent number: 12507650
Hazelnut Variety: StapN7-6 (1st Generation Selection)
Issued: 12/30/2025
Inventors: Lois Braun Jason Fischbach;
Patent number: PP37182
Human or Animal Health Sciences
Co-receptor Affinity Enhanced MHC Molecules
Issued: 1/7/2025
Inventors: Marc Jenkins; T Dileepan; Deepali Malhotra
Patent number: 12187781
Enhanced Methods for Microbiota Therapy in the Treatment of Autism Spectrum Disorders
Issued: 1/7/2025
Inventors: Alexander Khoruts; Chris Staley; Matthew Hamilton; Michael Sadowsky
Patent number: 12186349
Percutaneous Method and Devices for Longer-lasting RFA Therapeutic Relief from Chronic Pain Symptoms
Issued: 1/14/2025
Inventors: Akshay Gupte; Bryan Clark; Bryce Beverlin; Catherine Taylor; David Wechter
Patent number: 12193727
Decellularized Biologically-engineered Tubular Grafts and Valves
Issued: 1/21/2025
Inventors: Lee Meier; Robert Tranquillo; Zeeshan Syedain
Patent number: 12201509
Novel Therapeutics for the Treatment of Glaucoma
Issued: 1/28/2025
Inventors: Gunda Georg; Michael Fautsch; Michael Walters; Peter Dosa
Patent number: 12209140
Surface Markers for Identification and Purification of Fibroadipogenic Progenitor Cells from Human Skeletal Muscle
Issued: 2/11/2025
Inventors: Abhijit Dandapat; Michael Kyba; Natalya Goloviznina; Ning Xie
Patent number: 12221629
Skin care formulations and skin cancer treatment
Issued: 2/25/2025
Inventors: Ann Bode; Eunmiri Roh; Zigang Dong
Patent number: 12233073
GvHD-associated, Inflammasome-mediated Loss of Function in Adoptively Transferred Myeloid-derived Suppressor Cells
Issued: 2/25/2025
Inventors: Brent Koehn; Bruce Blazar; Jeffrey Miller; Jenny Ting; Peter Murray; Robert Zeiser
Patent number: 12234480
Method to Prepare Descemets Membrane Endothelial Keratoplasty (DMEK) Tissue for Improved Graft Unscrolling
Issued: 3/25/2025
Inventors: David Hardten; Jeff Justin; Joshua Hou; Mark Hansen; Martin de la Presa; Peter Bedard
Patent number: 12257365
Derivation of Human T-(Progenitor) Cells from Human T-Cells Derived Induced Pluripotent Stem Cells (T-iPSCs)
Issued: 4/8/2025
Inventors: Beau Webber; Bruce Blazar; Dharmeshkumar Patel; Jakub Tolar
Patent number: 12270050
Anti-canine CD16 and Anti-CD64 mAb Variable Regions and Recombinant Immune Cell Engagers for canine immunotherapy
Issued: 4/8/2025
Inventors: Bruce Walcheck; Daniel Vallera; Jianming Wu
Patent number: 12269887
Breast Cancer Detection Using an Engineered B7-H3 Affibody Ligand
Issued: 4/15/2025
Inventors: Amelie Lutz; Ben Hackel; Juergen Willmann; Larry Stern; Lotfi Abou-Elkacem; Patrick Lown; Rakesh Bam
Patent number: 12274759
Lymphohematopoietic Engineering Using Cas9 Base Editors
Issued: 4/22/2025
Inventors: Beau Webber; Branden Moriarity; Cara-lin Lonetree; Emily Pomeroy; Micki Diers; Mitchell Kluesner; Walker Lahr
Patent number: 12281327
Remodelins, a New Class of Compounds to Prevent Airway Remodeling and to Prevent Fibrosis in Multiple Organs
Issued: 4/22/2025
Inventors: Bohao Chen; Chan Young Park; Chun Geun Lee; David Maloney; David McCormick; Diane Luci; Jack Elias; Jeffrey Fredberg; Jiaolong Wang; Julian Solway; Miguel Muzzio; Nickolai Dulin; Ramaswamy Krishnan; Stephen Byrn; Tera Lavoie
Patent number: 12281060
Retionoic Acid Receptor Antagonists as Male Contraceptive Agents
Issued: 4/22/2025
Inventors: Gunda Georg; Narsihmulu Cheryala
Patent number: 12281105
Intestinal Microbial Flora Reconstituent for Treatment of Clostridium difficile Associated Disease and Other Intestinal Maladies
Issued: 5/13/2025
Inventors: Alexa Weingarden; Alexander Khoruts; Matthew Hamilton; Michael Sadowsky
Patent number: 12295974
Intravenous Baclofen
Issued: 5/13/2025
Inventors: Adolfo Gomez; James Cloyd; John Schrogie; Linda Krach; Rob Tuohy; Robert Kriel; Stephen Tucker
Patent number: 12295929
CLEC12A Targeting Tri-specific Killer Engager (TriKE) for Targeting of Myeloid Malignancies
Issued: 6/3/2025
Inventors: Daniel Vallera; Jeffrey Miller; Martin Felices; Todd Lenvik
Patent number: 12319737
Predictive and Prognsotic Molecular Test for Response to Bevacizumab and Platinum Based Chemotherapy in Ovarian Cancer
Issued: 6/10/2025
Inventors: Boris Winterhoff; Constantin Aliferis; Jinhua Wang; Sisi Ma
Patent number: 12325879
Conformable Dual-mode Ultrasound Transducers for Neuromodulation
Issued: 6/17/2025
Inventors: Emad Ebbini
Patent number: 12329991
Hyperspectral Imaging as a Tool for Early Detection of Alzheimer's Disease (AD) and Screening of Potential Therapeutics/Prophylactics Against AD
Issued: 6/17/2025
Inventors: Robert Vince; Swati More
Patent number: 12329457
Treg Genome Engineering for Steroid and Calcineurin Inhibitor Resistance
Issued: 7/1/2025
Inventors: Bruce Blazar; Keli Hippen; Mark Osborn
Patent number: 12343397
Algorithm to Improve LVAD Implants
Issued: 7/1/2025
Inventors: Andrew Shaffer; Anthony Prisco; David Ramirez; Mikayle Holm; Paul Iaizzo
Patent number: 12343086
Hierarchical Optimization of Settings for Medical Devices
Issued: 7/1/2025
Inventors: Andrew Lamperski; David Darrow; Tay Netoff; Tyler Lekang; Zixi Zhao
Patent number: 12343540
Systems and methods for multimodal neural sensing
Issued: 7/8/2025
Inventors: Daniel Schulman; Leila Ghanbari; Michael McAlpine; Preston Donaldson; Sarah Swisher; Suhasa Bangalore Kodandaramaiah
Patent number: 12350010
Orthodontic Tooth Aligners with Fluorescent Speckles
Issued: 7/8/2025
Inventors: Alex Fok; Brent Larson; Brian Holmes; Ning Ye; Susan Mantell
Patent number: 12352557
Novel Adenovirus Vector Generating System Enabling Adenoviral Library Work
Issued: 7/8/2025
Inventors: Masato Yamamoto; Yoshiaki Miura
Patent number: 12351797
Embolic Delivery Catheter
Issued: 7/22/2025
Inventors: Ajay Gupta; Camden Sundin; Enio Perez Filho; Joshua Shafer; Kenneth Urbanski; Samuel Awes
Patent number: 12364485
Peptide Activation of Antimicrobial Memory T Cells to Elicit Anti-tumor Effects
Issued: 7/29/2025
Inventors: David Masopust; Vaiva Vezys
Patent number: 12370256
Multi-Echo Frequency-modulated Rabi Encoded Echoes (FREE) MRI
Issued: 7/29/2025
Inventors: Efrain Torres; Michael Garwood; Taylor Froelich
Patent number: 12372595
Rolling Shutter Compensation for Vision-aided Inertial Navigation
Issued: 8/5/2025
Inventors: Chao Guo; Stergios Roumeliotis
Patent number: 12379215
CXCR5 and CAR Transduction of CTL to Localize CTL to Follicles and Treat Disease
Issued: 8/12/2025
Inventors: Pamela Skinner
Patent number: 12384830
Methods for treating cancer
Issued: 8/12/2025
Inventors: Darko Bosnakovski; Michael Kyba
Patent number: 12383534
Descemet's Membrane Grafts for the Ocular Surface
Issued: 8/12/2025
Inventors: Ching Yuan; Joshua Hou; Peter Bedard
Patent number: 12383655
3D Printing of Organisms
Issued: 8/19/2025
Inventors: Guebum Han; John Bischof; Kanav Khosla; Kieran Smith; Michael McAlpine
Patent number: 12391004
Augmented Reality Transjugular Intrahepatic Portosystemic Shunt (AR-TIPS) Set and Other Interventional Devices
Issued: 9/2/2025
Inventors: Aaron Koenigsberg; Braden Eliason; Enio Perez Filho; Jafar Golzarian; Reza Talaie
Patent number: 12402955
Targeting Multiple Immune Checkpoint Blockades with a CD200 Peptide Inhibitor
Issued: 9/16/2025
Inventors: Michael Olin
Patent number: 12414983
Programmable Genetic Device for Synthetic Speciation and Genetic Biocontainment
Issued: 9/16/2025
Inventors: Maciej Maselko; Michael Smanski
Patent number: 12416011
Mitigating Injury During Cryosurgery Using Novel Cryoprotective Agents
Issued: 9/30/2025
Inventors: David Ramirez; Franz Schmidlin; John Bischof; Paul Iaizzo; Pegah Ranjbartehrani; Qi Shao
Patent number: 12426594
A System for Unattended Delivery of Cognitive Neuromodulation Therapy
Issued: 10/7/2025
Inventors: Jazmin Camchong; Kelvin Lim
Patent number: 12434049
Humanization of Mouse Monoclonal Antibody to Serpin B13
Issued: 10/14/2025
Inventors: Jan Czyzyk
Patent number: 12441811
Versatile Antimicrobial Hydrogels
Issued: 10/14/2025
Inventors: Conrado Aparicio; Sven-Ulrik Gorr; Zhou Ye
Patent number: 12441773
Transplant Tolerance Induction with Carbodiimide Treated Tolerizing Vaccine
Issued: 10/21/2025
Inventors: Bernhard Hering; Sabarinathan Ramachandran
Patent number: 12448437
Mitigating Injury During Cryosurgery Using Novel Cryoprotective Agents
Issued: 10/28/2025
Inventors: Alexandre Porcello; David Ramirez; Franz Schmidlin; John Bischof; Paul Iaizzo; Pegah Ranjbartehrani; Qi Shao
Patent number: 12453805
Detecting Trauma by Measuring Volatile Organic Compound (VOC) Changes
Issued: 10/28/2025
Inventors: Elizabeth Lusczek; Greg Beilman; Gregory Peterson; Kristine Mulier; Phil Buhlmann
Patent number: 12453480
A Device for the Production and Vitrification of Cryoprotectant Droplets for High-throughput Cryobanking of Biological Material
Issued: 11/4/2025
Inventors: John Bischof; Jonathan Daly; Kanav Khosla; Li Zhan; Mary Hagedorn; Nikolas Zuchowicz
Patent number: 12458016
Deep Brain Stimulators (DBS) for Treatment of Glioblastoma
Issued: 11/4/2025
Inventors: Clark Chen; Gregory Molnar; Sanjay Dhawan
Patent number: 12458800
Jaw Opening Diagnostic Instrument (JODI)
Issued: 11/4/2025
Inventors: Darren Seaney; David Nascene; Donald Nixdorf; Holly Hayden; John Bedford; Katelyn Fitzgerald; Viraj Rajanayagam
Patent number: 12458293
Genetically Modified Cells, Tissues, and Organs For Treating Disease
Issued: 11/11/2025
Inventors: Bernhard Hering; Christopher Burlak
Patent number: 12465029
Novel Transcatheter Valve
Issued: 11/11/2025
Inventors: Robert Tranquillo; Zeeshan Syedain
Patent number: 12465486
Prodrugs of Tetrahydrobiopterin and Analogs of MitoTEMPO for the Treatment of Diastolic Dysfunction
Issued: 11/18/2025
Inventors: Gunda Georg; Narsihmulu Cheryala; Samuel Dudley; Sudhakar Jakkaraj
Patent number: 12473313
RISNA: Risk-free in situ Non Animal Surrogate Assay for ASFV
Issued: 12/2/2025
Inventors: Declan Schroeder
Patent number: 12486526
Coordinated Noninvasive Electrical and Ultrasound Stimulation of Peripheral Nerves and Spleen to Treat Inflammation and Autoimmune Disorders
Issued: 12/16/2025
Inventors: Claire Kaiser; Daniel Zachs; Hubert Lim
Patent number: 12496447
Production of Monoclonal Antibodies for Detection of Mycoplasma hyopneumoniae
Issued: 12/16/2025
Inventors: Maria Pieters; Maxim Cheeran; Venkatramana Divana Krishna Bhat
Patent number: 12497444
Quantitative Acoustic Nonlinearity Paremeter Imaging Using Pulse-Echo Ultrasound
Issued: 12/23/2025
Inventors: Abhishek Sahoo; Emad Ebbini; Nayef Alshamlan
Patent number: 12502160
Peptide Activation of Resident Memory T Cells for Cancer Immunotherapy
Issued: 12/23/2025
Inventors: David Masopust; Vaiva Vezys
Patent number: 12502406